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Abnormal electrophysiology of sinoatrial node origin

MedGen UID:
868812
•Concept ID:
C4023222
•
Anatomical Abnormality
HPO: HP:0011702

Definition

An abnormality of the sinoatrial (SA) node in the right atrium. THe SA node acts as the pacemaker of the heart. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal electrophysiology of sinoatrial node origin

Conditions with this feature

Intellectual disability, keratoconus, febrile seizures, and sinoatrial block
MedGen UID:
324455
•Concept ID:
C1836202
•
Disease or Syndrome
See: Condition Record
Sinus node disease and myopia
MedGen UID:
401121
•Concept ID:
C1866960
•
Disease or Syndrome
See: Condition Record
Intellectual disability, keratoconus, febrile seizures, and sinoatrial block
Sinus node disease and myopia

Recent clinical studies

Etiology

Bradyarrhythmias in Congenital Heart Disease.
Carlson SK, Patel AR, Chang PM
Card Electrophysiol Clin 2017 Jun;9(2):177-187. Epub 2017 Mar 22 doi: 10.1016/j.ccep.2017.02.002. PMID: 28457234
Atrial tachycardia originating from the pulmonary vein: clinical, electrocardiographic, and differential electrophysiologic characteristics.
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Clinical and electrophysiologic spectrum of fascicular tachycardias.
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Catheter mapping during sinus rhythm: relation of local electrogram duration to ventricular tachycardia cycle length.
Cassidy DM, Vassallo JA, Buxton AE, Doherty JU, Marchlinski FE, Josephson ME
Am J Cardiol 1985 Mar 1;55(6):713-6. doi: 10.1016/0002-9149(85)90142-0. PMID: 3976514
Electrophysiology and indications for pacing in the '80's.
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Diagnosis

Three-dimensional mapping and intracardiac echocardiography in the treatment of sinoatrial nodal tachycardias.
Nagarakanti R, Saksena S
J Interv Card Electrophysiol 2016 Jun;46(1):55-61. Epub 2015 Nov 25 doi: 10.1007/s10840-015-0072-7. PMID: 26607480
Atrial tachycardia originating from the pulmonary vein: clinical, electrocardiographic, and differential electrophysiologic characteristics.
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Supraventricular tachyarrhythmias involving the sinus node: clinical and electrophysiologic characteristics.
Cossú SF, Steinberg JS
Prog Cardiovasc Dis 1998 Jul-Aug;41(1):51-63. doi: 10.1016/s0033-0620(98)80022-4. PMID: 9717859
Sinus node shift after the Senning procedure compared with the Mustard procedure for transposition of the great arteries.
Byrum CJ, Bove EL, Sondheimer HM, Kavey RE, Blackman MS
Am J Cardiol 1987 Aug 1;60(4):346-50. doi: 10.1016/0002-9149(87)90240-2. PMID: 3618494
Electrophysiology and indications for pacing in the '80's.
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Therapy

Supraventricular tachyarrhythmias involving the sinus node: clinical and electrophysiologic characteristics.
Cossú SF, Steinberg JS
Prog Cardiovasc Dis 1998 Jul-Aug;41(1):51-63. doi: 10.1016/s0033-0620(98)80022-4. PMID: 9717859
Clinical and electrophysiologic spectrum of fascicular tachycardias.
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Electrophysiology and indications for pacing in the '80's.
Lüderitz B
Pacing Clin Electrophysiol 1982 Jul;5(4):548-60. doi: 10.1111/j.1540-8159.1982.tb02277.x. PMID: 6180398

Prognosis

Atrial tachycardia originating from the pulmonary vein: clinical, electrocardiographic, and differential electrophysiologic characteristics.
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413
Clinical and electrophysiologic spectrum of fascicular tachycardias.
Gonzalez RP, Scheinman MM, Lesh MD, Helmy I, Torres V, Van Hare GF
Am Heart J 1994 Jul;128(1):147-56. doi: 10.1016/0002-8703(94)90021-3. PMID: 8017268
Catheter mapping during sinus rhythm: relation of local electrogram duration to ventricular tachycardia cycle length.
Cassidy DM, Vassallo JA, Buxton AE, Doherty JU, Marchlinski FE, Josephson ME
Am J Cardiol 1985 Mar 1;55(6):713-6. doi: 10.1016/0002-9149(85)90142-0. PMID: 3976514

Clinical prediction guides

Atrial tachycardia originating from the pulmonary vein: clinical, electrocardiographic, and differential electrophysiologic characteristics.
Bazán V, Rodríguez-Font E, Viñolas X, Guerra JM, Bruguera-Cortada J, Martí-Almor J
Rev Esp Cardiol 2010 Feb;63(2):149-55. doi: 10.1016/s1885-5857(10)70032-3. PMID: 20109413

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