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Abnormal corpus striatum morphology

MedGen UID:
869185
•Concept ID:
C4023607
•
Anatomical Abnormality
Synonym: Abnormality of the striatum
 
HPO: HP:0010994

Definition

Abnormality of the striatum, which is the largest nucleus of the basal ganglia, comprising the caudate, putamen and ventral striatum, including the nucleus accumbens. [from HPO]

Conditions with this feature

Striatal degeneration, autosomal dominant 2
MedGen UID:
934758
•Concept ID:
C4310791
•
Disease or Syndrome
Autosomal dominant striatal degeneration-2 is a neurologic disorder characterized by hyperkinetic movements, mainly chorea, resulting from dysfunction of the basal ganglia. Although symptoms appear in the first decade, the disorder is not progressive (summary by Mencacci et al., 2016). For a discussion of genetic heterogeneity of ADSD, see ADSD1 (609161).
See: Condition Record
Striatal degeneration, autosomal dominant 2

Professional guidelines

PubMed

Lithium treatment impacts nucleus accumbens shape in bipolar disorder.
Vecchio D, Piras F, Piras F, Banaj N, Janiri D, Simonetti A, Sani G, Spalletta G
Neuroimage Clin 2020;25:102167. Epub 2020 Jan 10 doi: 10.1016/j.nicl.2020.102167. PMID: 31972398Free PMC Article
Levodopa treatment and dendritic spine pathology.
Nishijima H, Ueno T, Funamizu Y, Ueno S, Tomiyama M
Mov Disord 2018 Jul;33(6):877-888. Epub 2017 Sep 7 doi: 10.1002/mds.27172. PMID: 28880414Free PMC Article
Surgical treatment of Parkinson's disease.
Obeso JA, Rodríguez MC, Gorospe A, Guridi J, Alvarez L, Macias R
Baillieres Clin Neurol 1997 Apr;6(1):125-45. PMID: 9426872

Recent clinical studies

Etiology

Neuro-Immune Cross-Talk in the Striatum: From Basal Ganglia Physiology to Circuit Dysfunction.
Mancini A, Ghiglieri V, Parnetti L, Calabresi P, Di Filippo M
Front Immunol 2021;12:644294. Epub 2021 Apr 19 doi: 10.3389/fimmu.2021.644294. PMID: 33953715Free PMC Article
Increased insula-putamen connectivity in X-linked dystonia-parkinsonism.
Blood AJ, Waugh JL, Münte TF, Heldmann M, Domingo A, Klein C, Breiter HC, Lee LV, Rosales RL, Brüggemann N
Neuroimage Clin 2018;17:835-846. Epub 2017 Oct 28 doi: 10.1016/j.nicl.2017.10.025. PMID: 29527488Free PMC Article
Postural & striatal deformities in Parkinson`s disease: Are these rare?
Pandey S, Garg H
Indian J Med Res 2016 Jan;143(1):11-7. doi: 10.4103/0971-5916.178577. PMID: 26997007Free PMC Article
The dopamine hypothesis of schizophrenia: version III--the final common pathway.
Howes OD, Kapur S
Schizophr Bull 2009 May;35(3):549-62. Epub 2009 Mar 26 doi: 10.1093/schbul/sbp006. PMID: 19325164Free PMC Article
Caudate infarcts.
Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, Gorelick PB, Helgason C, Hier DB
Arch Neurol 1990 Feb;47(2):133-43. doi: 10.1001/archneur.1990.00530020029011. PMID: 2405818

Diagnosis

Diabetic striatopathy: a case report.
Guan Y, Yuan L, Yuan L
Neurocase 2023 Jun;29(3):90-91. Epub 2024 Feb 17 doi: 10.1080/13554794.2024.2317788. PMID: 38367007
"Diabetic striatopathy": clinical presentations, controversy, pathogenesis, treatments, and outcomes.
Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT
Sci Rep 2020 Jan 31;10(1):1594. doi: 10.1038/s41598-020-58555-w. PMID: 32005905Free PMC Article
Parkinson's disease: diagnosis.
Brooks DJ
Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S31-3. doi: 10.1016/S1353-8020(11)70012-8. PMID: 22166447
The dopamine hypothesis of schizophrenia: version III--the final common pathway.
Howes OD, Kapur S
Schizophr Bull 2009 May;35(3):549-62. Epub 2009 Mar 26 doi: 10.1093/schbul/sbp006. PMID: 19325164Free PMC Article
The corticostriatal pathway in Huntington's disease.
Cepeda C, Wu N, André VM, Cummings DM, Levine MS
Prog Neurobiol 2007 Apr;81(5-6):253-71. Epub 2006 Dec 13 doi: 10.1016/j.pneurobio.2006.11.001. PMID: 17169479Free PMC Article

Therapy

Potential mechanisms for phencyclidine/ketamine-induced brain structural alterations and behavioral consequences.
Wang C, Inselman A, Liu S, Liu F
Neurotoxicology 2020 Jan;76:213-219. Epub 2019 Dec 5 doi: 10.1016/j.neuro.2019.12.005. PMID: 31812709
Levodopa treatment and dendritic spine pathology.
Nishijima H, Ueno T, Funamizu Y, Ueno S, Tomiyama M
Mov Disord 2018 Jul;33(6):877-888. Epub 2017 Sep 7 doi: 10.1002/mds.27172. PMID: 28880414Free PMC Article
Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease.
Obeso JA, Rodríguez-Oroz MC, Benitez-Temino B, Blesa FJ, Guridi J, Marin C, Rodriguez M
Mov Disord 2008;23 Suppl 3:S548-59. doi: 10.1002/mds.22062. PMID: 18781672
Parkinsonism. Multiple system atrophy.
Wenning GK, Quinn NP
Baillieres Clin Neurol 1997 Apr;6(1):187-204. PMID: 9426875

Prognosis

Putamen Structure and Function in Familial Risk for Depression: A Multimodal Imaging Study.
Talati A, van Dijk MT, Pan L, Hao X, Wang Z, Gameroff M, Dong Z, Kayser J, Shankman S, Wickramaratne PJ, Posner J, Weissman MM
Biol Psychiatry 2022 Dec 15;92(12):932-941. Epub 2022 Jul 16 doi: 10.1016/j.biopsych.2022.06.035. PMID: 36038379Free PMC Article
Kernicterus in preterm infants.
Okumura A, Kidokoro H, Shoji H, Nakazawa T, Mimaki M, Fujii K, Oba H, Shimizu T
Pediatrics 2009 Jun;123(6):e1052-8. Epub 2009 May 11 doi: 10.1542/peds.2008-2791. PMID: 19433515
Pallidal stimulation for dystonia.
Lozano AM, Abosch A
Adv Neurol 2004;94:301-8. PMID: 14509687
Arteries of the insula.
Türe U, Yaşargil MG, Al-Mefty O, Yaşargil DC
J Neurosurg 2000 Apr;92(4):676-87. doi: 10.3171/jns.2000.92.4.0676. PMID: 10761659
Glycogenosis type VIII.
Kornfeld M, LeBaron M
J Neuropathol Exp Neurol 1984 Nov;43(6):568-79. doi: 10.1097/00005072-198411000-00002. PMID: 6594438

Clinical prediction guides

Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia.
Eskow Jaunarajs KL, Bonsi P, Chesselet MF, Standaert DG, Pisani A
Prog Neurobiol 2015 Apr;127-128:91-107. Epub 2015 Feb 17 doi: 10.1016/j.pneurobio.2015.02.002. PMID: 25697043Free PMC Article
The impairment of cholesterol metabolism in Huntington disease.
Leoni V, Caccia C
Biochim Biophys Acta 2015 Aug;1851(8):1095-105. Epub 2015 Jan 14 doi: 10.1016/j.bbalip.2014.12.018. PMID: 25596342
The neuroanatomy and neurochemistry of schizophrenia.
Weickert CS, Kleinman JE
Psychiatr Clin North Am 1998 Mar;21(1):57-75. doi: 10.1016/s0193-953x(05)70361-0. PMID: 9551491
Glycogenosis type VIII.
Kornfeld M, LeBaron M
J Neuropathol Exp Neurol 1984 Nov;43(6):568-79. doi: 10.1097/00005072-198411000-00002. PMID: 6594438

Recent systematic reviews

Resting-state fMRI in depressive and (hypo)manic mood states in bipolar disorders: A systematic review.
Claeys EHI, Mantingh T, Morrens M, Yalin N, Stokes PRA
Prog Neuropsychopharmacol Biol Psychiatry 2022 Mar 8;113:110465. Epub 2021 Nov 2 doi: 10.1016/j.pnpbp.2021.110465. PMID: 34736998
Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis.
Arnone D, Cavanagh J, Gerber D, Lawrie SM, Ebmeier KP, McIntosh AM
Br J Psychiatry 2009 Sep;195(3):194-201. doi: 10.1192/bjp.bp.108.059717. PMID: 19721106
Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies.
Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM
Eur Psychiatry 2008 Jun;23(4):289-99. Epub 2007 Aug 31 doi: 10.1016/j.eurpsy.2007.05.006. PMID: 17765485

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