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Abnormal corpus striatum morphology

MedGen UID:
869185
•Concept ID:
C4023607
•
Anatomical Abnormality
Synonym: Abnormality of the striatum
 
HPO: HP:0010994

Definition

Abnormality of the striatum, which is the largest nucleus of the basal ganglia, comprising the caudate, putamen and ventral striatum, including the nucleus accumbens. [from HPO]

Conditions with this feature

Striatal degeneration, autosomal dominant 2
MedGen UID:
934758
•Concept ID:
C4310791
•
Disease or Syndrome
Autosomal dominant striatal degeneration-2 is a neurologic disorder characterized by hyperkinetic movements, mainly chorea, resulting from dysfunction of the basal ganglia. Although symptoms appear in the first decade, the disorder is not progressive (summary by Mencacci et al., 2016). For a discussion of genetic heterogeneity of ADSD, see ADSD1 (609161).
See: Condition Record
Striatal degeneration, autosomal dominant 2

Professional guidelines

PubMed

Unilateral thalamic Vim and GPi stimulation for the treatment of Holmes' tremor caused by midbrain cavernoma: case report and review of the literature.
Aydin S, Abuzayed B, Kiziltan G, Gunduz A, Yagci S, Mengi M, Kizilkilic O, Uzan M, Hanci M
J Neurol Surg A Cent Eur Neurosurg 2013 Jul;74(4):271-6. Epub 2013 Jan 14 doi: 10.1055/s-0032-1322549. PMID: 23319330
The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment.
Weiner I
Psychopharmacology (Berl) 2003 Sep;169(3-4):257-97. Epub 2003 Feb 25 doi: 10.1007/s00213-002-1313-x. PMID: 12601500
Surgical treatment of Parkinson's disease.
Obeso JA, Rodríguez MC, Gorospe A, Guridi J, Alvarez L, Macias R
Baillieres Clin Neurol 1997 Apr;6(1):125-45. PMID: 9426872

Recent clinical studies

Etiology

Neuro-Immune Cross-Talk in the Striatum: From Basal Ganglia Physiology to Circuit Dysfunction.
Mancini A, Ghiglieri V, Parnetti L, Calabresi P, Di Filippo M
Front Immunol 2021;12:644294. Epub 2021 Apr 19 doi: 10.3389/fimmu.2021.644294. PMID: 33953715Free PMC Article
Characterizing the Subcortical Structures in Youth with Congenital Heart Disease.
Fontes K, Courtin F, Rohlicek CV, Saint-Martin C, Gilbert G, Easson K, Majnemer A, Marelli A, Chakravarty MM, Brossard-Racine M
AJNR Am J Neuroradiol 2020 Aug;41(8):1503-1508. Epub 2020 Jul 23 doi: 10.3174/ajnr.A6667. PMID: 32719093Free PMC Article
The dopamine hypothesis of schizophrenia: version III--the final common pathway.
Howes OD, Kapur S
Schizophr Bull 2009 May;35(3):549-62. Epub 2009 Mar 26 doi: 10.1093/schbul/sbp006. PMID: 19325164Free PMC Article
Pallidal stimulation for dystonia.
Lozano AM, Abosch A
Adv Neurol 2004;94:301-8. PMID: 14509687
Caudate infarcts.
Caplan LR, Schmahmann JD, Kase CS, Feldmann E, Baquis G, Greenberg JP, Gorelick PB, Helgason C, Hier DB
Arch Neurol 1990 Feb;47(2):133-43. doi: 10.1001/archneur.1990.00530020029011. PMID: 2405818

Diagnosis

"Diabetic striatopathy": clinical presentations, controversy, pathogenesis, treatments, and outcomes.
Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT
Sci Rep 2020 Jan 31;10(1):1594. doi: 10.1038/s41598-020-58555-w. PMID: 32005905Free PMC Article
Postural & striatal deformities in Parkinson`s disease: Are these rare?
Pandey S, Garg H
Indian J Med Res 2016 Jan;143(1):11-7. doi: 10.4103/0971-5916.178577. PMID: 26997007Free PMC Article
Parkinson's disease: diagnosis.
Brooks DJ
Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S31-3. doi: 10.1016/S1353-8020(11)70012-8. PMID: 22166447
The dopamine hypothesis of schizophrenia: version III--the final common pathway.
Howes OD, Kapur S
Schizophr Bull 2009 May;35(3):549-62. Epub 2009 Mar 26 doi: 10.1093/schbul/sbp006. PMID: 19325164Free PMC Article
The corticostriatal pathway in Huntington's disease.
Cepeda C, Wu N, André VM, Cummings DM, Levine MS
Prog Neurobiol 2007 Apr;81(5-6):253-71. Epub 2006 Dec 13 doi: 10.1016/j.pneurobio.2006.11.001. PMID: 17169479Free PMC Article

Therapy

Motor complications in Parkinson's disease: Striatal molecular and electrophysiological mechanisms of dyskinesias.
Picconi B, Hernández LF, Obeso JA, Calabresi P
Mov Disord 2018 Jul;33(6):867-876. Epub 2017 Dec 8 doi: 10.1002/mds.27261. PMID: 29219207
Levodopa treatment and dendritic spine pathology.
Nishijima H, Ueno T, Funamizu Y, Ueno S, Tomiyama M
Mov Disord 2018 Jul;33(6):877-888. Epub 2017 Sep 7 doi: 10.1002/mds.27172. PMID: 28880414Free PMC Article
Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease.
Obeso JA, Rodríguez-Oroz MC, Benitez-Temino B, Blesa FJ, Guridi J, Marin C, Rodriguez M
Mov Disord 2008;23 Suppl 3:S548-59. doi: 10.1002/mds.22062. PMID: 18781672
Parkinsonism. Multiple system atrophy.
Wenning GK, Quinn NP
Baillieres Clin Neurol 1997 Apr;6(1):187-204. PMID: 9426875

Prognosis

Interaction between ventricular expansion and structural changes in the corpus callosum and putamen in males with FMR1 normal and premutation alleles.
Wang JY, Hessl D, Tassone F, Kim K, Hagerman RJ, Rivera SM
Neurobiol Aging 2020 Feb;86:27-38. Epub 2019 Sep 24 doi: 10.1016/j.neurobiolaging.2019.09.009. PMID: 31733943Free PMC Article
Specific language impairment is not specific to language: the procedural deficit hypothesis.
Ullman MT, Pierpont EI
Cortex 2005 Jun;41(3):399-433. doi: 10.1016/s0010-9452(08)70276-4. PMID: 15871604
Pallidal stimulation for dystonia.
Lozano AM, Abosch A
Adv Neurol 2004;94:301-8. PMID: 14509687
Arteries of the insula.
Türe U, Yaşargil MG, Al-Mefty O, Yaşargil DC
J Neurosurg 2000 Apr;92(4):676-87. doi: 10.3171/jns.2000.92.4.0676. PMID: 10761659
Acute caudate vascular lesions.
Kumral E, Evyapan D, Balkir K
Stroke 1999 Jan;30(1):100-8. doi: 10.1161/01.str.30.1.100. PMID: 9880396

Clinical prediction guides

Exercise effects on depression: Possible neural mechanisms.
Gujral S, Aizenstein H, Reynolds CF 3rd, Butters MA, Erickson KI
Gen Hosp Psychiatry 2017 Nov;49:2-10. doi: 10.1016/j.genhosppsych.2017.04.012. PMID: 29122145Free PMC Article
Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia.
Eskow Jaunarajs KL, Bonsi P, Chesselet MF, Standaert DG, Pisani A
Prog Neurobiol 2015 Apr;127-128:91-107. Epub 2015 Feb 17 doi: 10.1016/j.pneurobio.2015.02.002. PMID: 25697043Free PMC Article
The impairment of cholesterol metabolism in Huntington disease.
Leoni V, Caccia C
Biochim Biophys Acta 2015 Aug;1851(8):1095-105. Epub 2015 Jan 14 doi: 10.1016/j.bbalip.2014.12.018. PMID: 25596342
Basal ganglia and thalamic morphology in schizophrenia and bipolar disorder.
Womer FY, Wang L, Alpert KI, Smith MJ, Csernansky JG, Barch DM, Mamah D
Psychiatry Res 2014 Aug 30;223(2):75-83. Epub 2014 Jun 6 doi: 10.1016/j.pscychresns.2014.05.017. PMID: 24957866Free PMC Article
Pallidal stimulation for dystonia.
Lozano AM, Abosch A
Adv Neurol 2004;94:301-8. PMID: 14509687

Recent systematic reviews

Resting-state fMRI in depressive and (hypo)manic mood states in bipolar disorders: A systematic review.
Claeys EHI, Mantingh T, Morrens M, Yalin N, Stokes PRA
Prog Neuropsychopharmacol Biol Psychiatry 2022 Mar 8;113:110465. Epub 2021 Nov 2 doi: 10.1016/j.pnpbp.2021.110465. PMID: 34736998
Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis.
Arnone D, Cavanagh J, Gerber D, Lawrie SM, Ebmeier KP, McIntosh AM
Br J Psychiatry 2009 Sep;195(3):194-201. doi: 10.1192/bjp.bp.108.059717. PMID: 19721106
Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies.
Stanfield AC, McIntosh AM, Spencer MD, Philip R, Gaur S, Lawrie SM
Eur Psychiatry 2008 Jun;23(4):289-99. Epub 2007 Aug 31 doi: 10.1016/j.eurpsy.2007.05.006. PMID: 17765485

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