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Hamartoma of the eye

MedGen UID:
869362
Concept ID:
C4023788
Neoplastic Process
HPO: HP:0010568

Definition

A hamartoma (disordered proliferation of mature tissues) which can originate from any tissue of the eye. [from HPO]

Professional guidelines

PubMed

Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
Thavikulwat AT, Edward DP, AlDarrab A, Vajaranant TS
J Neurosci Res 2019 Jan;97(1):57-69. Epub 2018 Apr 1 doi: 10.1002/jnr.24241. PMID: 29607552
Au KS, Williams AT, Roach ES, Batchelor L, Sparagana SP, Delgado MR, Wheless JW, Baumgartner JE, Roa BB, Wilson CM, Smith-Knuppel TK, Cheung MY, Whittemore VH, King TM, Northrup H
Genet Med 2007 Feb;9(2):88-100. doi: 10.1097/gim.0b013e31803068c7. PMID: 17304050

Recent clinical studies

Etiology

Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
Douglas KAA, Douglas VP, Cestari DM
Curr Opin Ophthalmol 2019 Nov;30(6):434-442. doi: 10.1097/ICU.0000000000000609. PMID: 31464700
Tsang SH, Sharma T
Adv Exp Med Biol 2018;1085:201-203. doi: 10.1007/978-3-319-95046-4_42. PMID: 30578515
Shields JA, Shields CL
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):215-223. doi: 10.22608/APO.201705. PMID: 28399346
Asch S, Sugarman JL
Handb Clin Neurol 2015;132:291-316. doi: 10.1016/B978-0-444-62702-5.00022-6. PMID: 26564089

Diagnosis

Salles DC, Asrani K, Woo J, Vidotto T, Liu HB, Vidal I, Matoso A, Netto GJ, Argani P, Lotan TL
J Pathol 2022 Jun;257(2):158-171. Epub 2022 Mar 29 doi: 10.1002/path.5875. PMID: 35072947Free PMC Article
Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
Javaid A, Shabbir Z, Din IU
J Pak Med Assoc 2019 Mar;69(3):445. PMID: 30890846
Moog U
J Med Genet 2009 Nov;46(11):721-9. Epub 2009 Jul 1 doi: 10.1136/jmg.2009.066068. PMID: 19574261
Au KS, Williams AT, Roach ES, Batchelor L, Sparagana SP, Delgado MR, Wheless JW, Baumgartner JE, Roa BB, Wilson CM, Smith-Knuppel TK, Cheung MY, Whittemore VH, King TM, Northrup H
Genet Med 2007 Feb;9(2):88-100. doi: 10.1097/gim.0b013e31803068c7. PMID: 17304050

Therapy

Wu F, McGarrey MP, Geenen KR, Skalet AH, Guillot FH, Wilson JL, Shah AS, Gonzalez E, Thiele EA, Kim IK, Aronow ME
Ophthalmol Retina 2022 May;6(5):411-420. Epub 2022 Jan 8 doi: 10.1016/j.oret.2022.01.003. PMID: 35007768
van der Poest Clement E, Jansen FE, Braun KPJ, Peters JM
Paediatr Drugs 2020 Feb;22(1):73-84. doi: 10.1007/s40272-019-00376-0. PMID: 31912454
Mennel S, Barbazetto I, Meyer CH, Peter S, Stur M
Ophthalmologica 2007;221(4):216-26. doi: 10.1159/000101922. PMID: 17579286
Thompson CR, Lessell S
Int Ophthalmol Clin 1997 Fall;37(4):261-79. doi: 10.1097/00004397-199703740-00021. PMID: 9429946
Bolande RP
Perspect Pediatr Pathol 1976;3:145-83. PMID: 184428

Prognosis

Touraine R, Hauet Q, Harzallah I, Baruteau AE
Arch Pediatr 2022 Dec;29(5S):5S3-5S7. doi: 10.1016/S0929-693X(22)00283-4. PMID: 36585068
Wang W, Chen L
Retina 2017 Apr;37(4):611-621. doi: 10.1097/IAE.0000000000001374. PMID: 27820777
Hodgson N, Kinori M, Goldbaum MH, Robbins SL
Clin Exp Ophthalmol 2017 Jan;45(1):81-86. Epub 2016 Sep 15 doi: 10.1111/ceo.12806. PMID: 27447981
Gawel J, Schwartz RA, Józwiak S
J Cutan Med Surg 2003 Jan-Feb;7(1):61-5. Epub 2002 Oct 9 doi: 10.1007/s10227-002-1142-x. PMID: 12362260
Wright JE, Sullivan TJ, Garner A, Wulc AE, Moseley IF
Ophthalmology 1997 Jun;104(6):905-13. doi: 10.1016/s0161-6420(97)30208-5. PMID: 9186428

Clinical prediction guides

Frazier TW, Busch RM, Klaas P, Lachlan K, Jeste S, Kolevzon A, Loth E, Harris J, Speer L, Pepper T, Anthony K, Graglia JM, Delagrammatikas CG, Bedrosian-Sermone S, Smith-Hicks C, Huba K, Longyear R, Green-Snyder L, Shic F, Sahin M, Eng C, Hardan AY, Uljarević M
Am J Med Genet C Semin Med Genet 2023 Sep;193(3):e32058. Epub 2023 Aug 3 doi: 10.1002/ajmg.c.32058. PMID: 37534867Free PMC Article
Mirzayev I, Gündüz AK
Turk J Ophthalmol 2022 Dec 28;52(6):421-431. doi: 10.4274/tjo.galenos.2022.25979. PMID: 36578224Free PMC Article
Salles DC, Asrani K, Woo J, Vidotto T, Liu HB, Vidal I, Matoso A, Netto GJ, Argani P, Lotan TL
J Pathol 2022 Jun;257(2):158-171. Epub 2022 Mar 29 doi: 10.1002/path.5875. PMID: 35072947Free PMC Article
Furdová A, Babál P
Cesk Slov Oftalmol 2020 Spring;76(2):62-67. doi: 10.31348/2020/13. PMID: 33126800
Au KS, Williams AT, Roach ES, Batchelor L, Sparagana SP, Delgado MR, Wheless JW, Baumgartner JE, Roa BB, Wilson CM, Smith-Knuppel TK, Cheung MY, Whittemore VH, King TM, Northrup H
Genet Med 2007 Feb;9(2):88-100. doi: 10.1097/gim.0b013e31803068c7. PMID: 17304050

Recent systematic reviews

Jia RB, Wang YF, Jia RB
Eur Rev Med Pharmacol Sci 2023 Nov;27(21):10313-10321. doi: 10.26355/eurrev_202311_34306. PMID: 37975355
Mason KA, Navaratnam A, Theodorakopoulou E, Chokkalingam PG
J Otolaryngol Head Neck Surg 2015 Jul 3;44(1):28. doi: 10.1186/s40463-015-0077-3. PMID: 26138824Free PMC Article

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