Tapered metacarpals

MedGen UID:: 870639
•Concept ID:: C4025091
•: Finding

Synonym:	Tapered long bones of hand

HPO:	HP:0006108

Definition

Metacarpal that becomes thinner toward the distal end. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVTapered metacarpals

Phenotypic abnormality
- Abnormality of limbs
  - Abnormality of the upper limb
    - Abnormal upper limb bone morphology
      - Abnormal metacarpal morphology
        Tapered metacarpals

Conditions with this feature

Spondyloepiphyseal dysplasia, Cantu type

MedGen UID:: 435975
•Concept ID:: C2673649
•: Disease or Syndrome

An extremely rare type of spondyloepiphyseal dysplasia described in about 5 patients to date with clinical signs including short stature, peculiar facies with blepharophimosis, upward slanted eyes, abundant eyebrows and eyelashes, coarse voice, and short hands and feet.

See: Condition Record

Spondyloepiphyseal dysplasia, Cantu type

Recent clinical studies

Therapy

Changes in hand and generalised bone mineral density in patients with recent-onset rheumatoid arthritis.

Güler-Yüksel M, Allaart CF, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, van Groenendael JH, Mallée C, de Bois MH, Breedveld FC, Dijkmans BA, Lems WF
Ann Rheum Dis 2009 Mar;68(3):330-6. Epub 2008 Mar 28 doi: 10.1136/ard.2007.086348. PMID: 18375540

Improvement of the bone-pin interface strength in osteoporotic bone with use of hydroxyapatite-coated tapered external-fixation pins. A prospective, randomized clinical study of wrist fractures.

Moroni A, Faldini C, Marchetti S, Manca M, Consoli V, Giannini S
J Bone Joint Surg Am 2001 May;83(5):717-21. doi: 10.2106/00004623-200105000-00010. PMID: 11379741

Orthofix external fixation of distal radius fractures: complications associated with screw size.

Gainor BJ, Moussa F
J South Orthop Assoc 1994 Winter;3(4):299-302. PMID: 8746383

See all (3)