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Cherry hemangioma

MedGen UID:
87470
•Concept ID:
C0343082
•
Neoplastic Process
Synonyms: Blood spots on skin; Campbell de Morgan angioma; Campbell de Morgan spot; Campbell de Morgan Spot; Cherry angioma; Cherry Angioma; cherry angioma; Cherry Hemangioma; cherry hemangioma; De Morgan's spots; Senile angioma; Senile Angioma; Senile ectasia; Senile Hemangioma; Senile hemangioma; Senile naevus of skin; Senile nevus of skin
SNOMED CT: Campbell de Morgan spot (5050001); Campbell de Morgan angioma (5050001); Blood spots on skin (5050001); Senile nevus of skin (5050001); Senile angioma (5050001); Senile ectasia (5050001); Cherry angioma (5050001); De Morgan's spots (5050001)
 
Monarch Initiative: MONDO:0002323

Definition

A capillary hemangioma of the skin, presenting as a red papular lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCherry hemangioma

Professional guidelines

PubMed

Evaluation and management of benign tumors of the eye and eyelid.
Brown R, Fard S, Feng P, Kerr PE
Clin Dermatol 2024 Jul-Aug;42(4):343-350. Epub 2024 Jan 26 doi: 10.1016/j.clindermatol.2024.01.005. PMID: 38281689
Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464
The pulsed-dye laser for treatment of cutaneous conditions.
Bernstein EF
G Ital Dermatol Venereol 2009 Oct;144(5):557-72. PMID: 19834434

Recent clinical studies

Etiology

Aberrant cytoplasmic connexin43 expression as a helpful marker in vascular neoplasms.
Frings VG, Goebeler M, Schilling B, Kneitz H
J Cutan Pathol 2021 Nov;48(11):1335-1341. Epub 2021 Jun 10 doi: 10.1111/cup.14066. PMID: 34021619
Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464
Thrombotic Hemangioma With Organizing/Anastomosing Features: Expanding the Spectrum of GNA-mutated Hemangiomas With a Predilection for the Skin of the Lower Abdominal Regions.
Liau JY, Lee JC, Tsai JH, Chen CC, Wang YH, Chung YC
Am J Surg Pathol 2020 Feb;44(2):255-262. doi: 10.1097/PAS.0000000000001392. PMID: 31633489
Is sclerotherapy useful for cherry angiomas?
Jairath V, Dayal S, Jain VK, Jindal N, Gogna P, Sehrawat M, Kaur S, Verma P
Dermatol Surg 2014 Sep;40(9):1022-7. doi: 10.1097/01.DSS.0000452631.83962.58. PMID: 25099289
The pulsed-dye laser for treatment of cutaneous conditions.
Bernstein EF
G Ital Dermatol Venereol 2009 Oct;144(5):557-72. PMID: 19834434

Diagnosis

Enhancing Cherry Hemangioma: A Mimic for Breast Cancer on Contrast-Enhanced Mammography.
Lu AH, Zuley ML, Berg WA
AJR Am J Roentgenol 2022 Jul;219(1):160-161. Epub 2022 Feb 9 doi: 10.2214/AJR.22.27363. PMID: 35138132
Aberrant cytoplasmic connexin43 expression as a helpful marker in vascular neoplasms.
Frings VG, Goebeler M, Schilling B, Kneitz H
J Cutan Pathol 2021 Nov;48(11):1335-1341. Epub 2021 Jun 10 doi: 10.1111/cup.14066. PMID: 34021619
Thrombotic Hemangioma With Organizing/Anastomosing Features: Expanding the Spectrum of GNA-mutated Hemangiomas With a Predilection for the Skin of the Lower Abdominal Regions.
Liau JY, Lee JC, Tsai JH, Chen CC, Wang YH, Chung YC
Am J Surg Pathol 2020 Feb;44(2):255-262. doi: 10.1097/PAS.0000000000001392. PMID: 31633489
Carbonic anhydrase is abundant in fenestrated capillaries of cherry hemangioma.
Eichhorn M, Jungkunz W, Wörl J, Marsch WC
Acta Derm Venereol 1994 Jan;74(1):51-3. doi: 10.2340/00015555745153. PMID: 7908484
Syringoma of the vulva: incidence, diagnosis, and cause of pruritus.
Young AW Jr, Herman EW, Tovell HM
Obstet Gynecol 1980 Apr;55(4):515-8. PMID: 7366908

Therapy

Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464
Is sclerotherapy useful for cherry angiomas?
Jairath V, Dayal S, Jain VK, Jindal N, Gogna P, Sehrawat M, Kaur S, Verma P
Dermatol Surg 2014 Sep;40(9):1022-7. doi: 10.1097/01.DSS.0000452631.83962.58. PMID: 25099289
The pulsed-dye laser for treatment of cutaneous conditions.
Bernstein EF
G Ital Dermatol Venereol 2009 Oct;144(5):557-72. PMID: 19834434

Prognosis

Thrombotic Hemangioma With Organizing/Anastomosing Features: Expanding the Spectrum of GNA-mutated Hemangiomas With a Predilection for the Skin of the Lower Abdominal Regions.
Liau JY, Lee JC, Tsai JH, Chen CC, Wang YH, Chung YC
Am J Surg Pathol 2020 Feb;44(2):255-262. doi: 10.1097/PAS.0000000000001392. PMID: 31633489
Utilization of Optical Coherence Tomography in the Evaluation of Cherry Hemangiomas.
Aldahan AS, Mlacker S, Shah VV, Chen LL, Nouri K, Grichnik JM
J Drugs Dermatol 2016 Jun 1;15(6):713-4. PMID: 27272077

Clinical prediction guides

Aberrant cytoplasmic connexin43 expression as a helpful marker in vascular neoplasms.
Frings VG, Goebeler M, Schilling B, Kneitz H
J Cutan Pathol 2021 Nov;48(11):1335-1341. Epub 2021 Jun 10 doi: 10.1111/cup.14066. PMID: 34021619
Utilization of Optical Coherence Tomography in the Evaluation of Cherry Hemangiomas.
Aldahan AS, Mlacker S, Shah VV, Chen LL, Nouri K, Grichnik JM
J Drugs Dermatol 2016 Jun 1;15(6):713-4. PMID: 27272077
Is sclerotherapy useful for cherry angiomas?
Jairath V, Dayal S, Jain VK, Jindal N, Gogna P, Sehrawat M, Kaur S, Verma P
Dermatol Surg 2014 Sep;40(9):1022-7. doi: 10.1097/01.DSS.0000452631.83962.58. PMID: 25099289
Carbonic anhydrase is abundant in fenestrated capillaries of cherry hemangioma.
Eichhorn M, Jungkunz W, Wörl J, Marsch WC
Acta Derm Venereol 1994 Jan;74(1):51-3. doi: 10.2340/00015555745153. PMID: 7908484

Recent systematic reviews

Treatment Modalities for Cherry Angiomas: A Systematic Review.
Buslach N, Foulad DP, Saedi N, Mesinkovska NA
Dermatol Surg 2020 Dec;46(12):1691-1697. doi: 10.1097/DSS.0000000000002791. PMID: 33252464

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