U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

High pulse pressure

MedGen UID:
886170
•Concept ID:
C0855323
•
Finding
HPO: HP:0030852

Definition

Increased amplitude of the pulse pressure (systolic blood pressure minus diastolic blood pressure). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHigh pulse pressure

Professional guidelines

PubMed

Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment.
Samsu N
Biomed Res Int 2021;2021:1497449. Epub 2021 Jul 8 doi: 10.1155/2021/1497449. PMID: 34307650Free PMC Article
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC Jr, Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA Sr, Williamson JD, Wright JT Jr
Hypertension 2018 Jun;71(6):e13-e115. Epub 2017 Nov 13 doi: 10.1161/HYP.0000000000000065. PMID: 29133356
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC Jr, Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA Sr, Williamson JD, Wright JT Jr
Hypertension 2018 Jun;71(6):1269-1324. Epub 2017 Nov 13 doi: 10.1161/HYP.0000000000000066. PMID: 29133354

Recent clinical studies

Etiology

The role of illness burden in theory of mind performance among older adults.
Walzak LC, Loken Thornton W
Exp Aging Res 2018 Oct-Dec;44(5):427-442. doi: 10.1080/0361073X.2018.1521494. PMID: 30355180
Neurocognitive disorder in hypertensive patients. Heart-Brain Study.
Vicario A, Cerezo GH, Del Sueldo M, Zilberman J, Pawluk SM, Lódolo N, De Cerchio AE, Ruffa RM, Plunkett R, Giuliano ME, Forcada P, Hauad S, Flores R; Heart-Brain Research Group in Argentina with the support of the Argentine Federation of Cardiology (FAC)
Hipertens Riesgo Vasc 2018 Oct-Dec;35(4):169-176. Epub 2018 Feb 15 doi: 10.1016/j.hipert.2018.01.004. PMID: 29456127
High pulse pressure is not associated with abnormal activation of the renin-angiotensin-aldosterone system in repaired aortic coarctation.
Pedersen TA, Pedersen EB, Munk K, Hjortdal VE, Emmertsen K, Andersen NH
J Hum Hypertens 2015 Apr;29(4):268-73. Epub 2014 Aug 28 doi: 10.1038/jhh.2014.75. PMID: 25355011
Hypertension in the elderly and the very old.
Casiglia E, Tikhonoff V, Pessina AC
Expert Rev Cardiovasc Ther 2009 Jun;7(6):659-65. doi: 10.1586/erc.09.17. PMID: 19505281
Optimal blood pressure level and best measurement procedure in hemodialysis patients.
Saint-Remy A, Krzesinski JM
Vasc Health Risk Manag 2005;1(3):235-44. PMID: 17319109Free PMC Article

Diagnosis

Persistent High Pulse Pressure in Acute Non-Cardiogenic Ischemic Stroke as a Predictor of Neurological Deterioration and Recurrence of Ischemic Stroke: ADS Post-Hoc Analysis.
Ozawa T, Fujimoto S, Aoki J, Matsuzono K, Kimura K
J Atheroscler Thromb 2023 Nov 1;30(11):1703-1714. Epub 2023 Apr 20 doi: 10.5551/jat.64079. PMID: 37081614Free PMC Article
High pulse pressure is not associated with abnormal activation of the renin-angiotensin-aldosterone system in repaired aortic coarctation.
Pedersen TA, Pedersen EB, Munk K, Hjortdal VE, Emmertsen K, Andersen NH
J Hum Hypertens 2015 Apr;29(4):268-73. Epub 2014 Aug 28 doi: 10.1038/jhh.2014.75. PMID: 25355011
Associations among cerebral microbleeds, cerebral large-artery diseases and endothelial function.
Peng Q, Huang Y, Sun W, Xing H
Chin Med J (Engl) 2014;127(18):3204-8. PMID: 25266513
Optimal blood pressure level and best measurement procedure in hemodialysis patients.
Saint-Remy A, Krzesinski JM
Vasc Health Risk Manag 2005;1(3):235-44. PMID: 17319109Free PMC Article
Spurious systolic hypertension of youth: fit young men with elastic arteries.
Mahmud A, Feely J
Am J Hypertens 2003 Mar;16(3):229-32. doi: 10.1016/s0895-7061(02)03255-7. PMID: 12620702

Therapy

High pulse pressure predicts primary arteriovenous fistula failure within 1 year.
Wu CC, Hung HC, Kao TC, Hsin CH, Yu SY, Hsieh HC, Ko PJ
J Vasc Access 2023 Nov;24(6):1349-1357. Epub 2022 Apr 8 doi: 10.1177/11297298211054797. PMID: 35394390
High pulse pressure is not associated with abnormal activation of the renin-angiotensin-aldosterone system in repaired aortic coarctation.
Pedersen TA, Pedersen EB, Munk K, Hjortdal VE, Emmertsen K, Andersen NH
J Hum Hypertens 2015 Apr;29(4):268-73. Epub 2014 Aug 28 doi: 10.1038/jhh.2014.75. PMID: 25355011
Hypertension in the elderly and the very old.
Casiglia E, Tikhonoff V, Pessina AC
Expert Rev Cardiovasc Ther 2009 Jun;7(6):659-65. doi: 10.1586/erc.09.17. PMID: 19505281
Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (> or =55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions.
Sweitzer NK, Lopatin M, Yancy CW, Mills RM, Stevenson LW
Am J Cardiol 2008 Apr 15;101(8):1151-6. Epub 2008 Feb 20 doi: 10.1016/j.amjcard.2007.12.014. PMID: 18394450Free PMC Article
Optimal blood pressure level and best measurement procedure in hemodialysis patients.
Saint-Remy A, Krzesinski JM
Vasc Health Risk Manag 2005;1(3):235-44. PMID: 17319109Free PMC Article

Prognosis

High pulse pressure predicts primary arteriovenous fistula failure within 1 year.
Wu CC, Hung HC, Kao TC, Hsin CH, Yu SY, Hsieh HC, Ko PJ
J Vasc Access 2023 Nov;24(6):1349-1357. Epub 2022 Apr 8 doi: 10.1177/11297298211054797. PMID: 35394390
High Pulse Pressure Decreases Cardiopulmonary Ability among Older Chinese Patients with Primary Hypertension.
Jin Y, Liu S, Lin M, Xu Y, Zhou S, Ye B, Lin S, Guan X, Wang L
Int Heart J 2022;63(6):1134-1140. doi: 10.1536/ihj.22-378. PMID: 36450553
Interactive Effects of Pulse Pressure and Tau Imaging on Longitudinal Cognition.
Weigand AJ, Macomber AJ, Walker KS, Edwards L, Thomas KR, Bangen KJ, Nation DA, Bondi MW; Alzheimer’s Disease Neuroimaging Initiative
J Alzheimers Dis 2022;89(2):633-640. doi: 10.3233/JAD-220026. PMID: 35938247Free PMC Article
The role of illness burden in theory of mind performance among older adults.
Walzak LC, Loken Thornton W
Exp Aging Res 2018 Oct-Dec;44(5):427-442. doi: 10.1080/0361073X.2018.1521494. PMID: 30355180
Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (> or =55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions.
Sweitzer NK, Lopatin M, Yancy CW, Mills RM, Stevenson LW
Am J Cardiol 2008 Apr 15;101(8):1151-6. Epub 2008 Feb 20 doi: 10.1016/j.amjcard.2007.12.014. PMID: 18394450Free PMC Article

Clinical prediction guides

High pulse pressure predicts primary arteriovenous fistula failure within 1 year.
Wu CC, Hung HC, Kao TC, Hsin CH, Yu SY, Hsieh HC, Ko PJ
J Vasc Access 2023 Nov;24(6):1349-1357. Epub 2022 Apr 8 doi: 10.1177/11297298211054797. PMID: 35394390
High Pulse Pressure Decreases Cardiopulmonary Ability among Older Chinese Patients with Primary Hypertension.
Jin Y, Liu S, Lin M, Xu Y, Zhou S, Ye B, Lin S, Guan X, Wang L
Int Heart J 2022;63(6):1134-1140. doi: 10.1536/ihj.22-378. PMID: 36450553
Interactive Effects of Pulse Pressure and Tau Imaging on Longitudinal Cognition.
Weigand AJ, Macomber AJ, Walker KS, Edwards L, Thomas KR, Bangen KJ, Nation DA, Bondi MW; Alzheimer’s Disease Neuroimaging Initiative
J Alzheimers Dis 2022;89(2):633-640. doi: 10.3233/JAD-220026. PMID: 35938247Free PMC Article
The role of illness burden in theory of mind performance among older adults.
Walzak LC, Loken Thornton W
Exp Aging Res 2018 Oct-Dec;44(5):427-442. doi: 10.1080/0361073X.2018.1521494. PMID: 30355180
Neurocognitive disorder in hypertensive patients. Heart-Brain Study.
Vicario A, Cerezo GH, Del Sueldo M, Zilberman J, Pawluk SM, Lódolo N, De Cerchio AE, Ruffa RM, Plunkett R, Giuliano ME, Forcada P, Hauad S, Flores R; Heart-Brain Research Group in Argentina with the support of the Argentine Federation of Cardiology (FAC)
Hipertens Riesgo Vasc 2018 Oct-Dec;35(4):169-176. Epub 2018 Feb 15 doi: 10.1016/j.hipert.2018.01.004. PMID: 29456127

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...