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Abnormal light-adapted single flash electroretinogram

MedGen UID:
892887
•Concept ID:
C4072962
•
Finding
HPO: HP:0030472

Recent clinical studies

Etiology

Electrophysiological measures of dysfunction in early-stage diabetic retinopathy: No correlation between cone phototransduction and oscillatory potential abnormalities.
McAnany JJ, Liu K, Park JC
Doc Ophthalmol 2020 Feb;140(1):31-42. Epub 2019 Sep 11 doi: 10.1007/s10633-019-09718-2. PMID: 31512016Free PMC Article
Cone Photoreceptor Dysfunction in Early-Stage Diabetic Retinopathy: Association Between the Activation Phase of Cone Phototransduction and the Flicker Electroretinogram.
McAnany JJ, Park JC
Invest Ophthalmol Vis Sci 2019 Jan 2;60(1):64-72. doi: 10.1167/iovs.18-25946. PMID: 30640972Free PMC Article
Expanded Retinal Disease Spectrum Associated With Autosomal Recessive Mutations in GUCY2D.
Stunkel ML, Brodie SE, Cideciyan AV, Pfeifer WL, Kennedy EL, Stone EM, Jacobson SG, Drack AV
Am J Ophthalmol 2018 Jun;190:58-68. Epub 2018 Mar 17 doi: 10.1016/j.ajo.2018.03.021. PMID: 29559409

Diagnosis

Electrophysiological measures of dysfunction in early-stage diabetic retinopathy: No correlation between cone phototransduction and oscillatory potential abnormalities.
McAnany JJ, Liu K, Park JC
Doc Ophthalmol 2020 Feb;140(1):31-42. Epub 2019 Sep 11 doi: 10.1007/s10633-019-09718-2. PMID: 31512016Free PMC Article
Cone Photoreceptor Dysfunction in Early-Stage Diabetic Retinopathy: Association Between the Activation Phase of Cone Phototransduction and the Flicker Electroretinogram.
McAnany JJ, Park JC
Invest Ophthalmol Vis Sci 2019 Jan 2;60(1):64-72. doi: 10.1167/iovs.18-25946. PMID: 30640972Free PMC Article
Expanded Retinal Disease Spectrum Associated With Autosomal Recessive Mutations in GUCY2D.
Stunkel ML, Brodie SE, Cideciyan AV, Pfeifer WL, Kennedy EL, Stone EM, Jacobson SG, Drack AV
Am J Ophthalmol 2018 Jun;190:58-68. Epub 2018 Mar 17 doi: 10.1016/j.ajo.2018.03.021. PMID: 29559409
Electroretinographic abnormalities in parents of patients with Leber congenital amaurosis who have heterozygous GUCY2D mutations.
Koenekoop RK, Fishman GA, Iannaccone A, Ezzeldin H, Ciccarelli ML, Baldi A, Sunness JS, Lotery AJ, Jablonski MM, Pittler SJ, Maumenee I
Arch Ophthalmol 2002 Oct;120(10):1325-30. doi: 10.1001/archopht.120.10.1325. PMID: 12365911
Assessing abnormal rod photoreceptor activity with the a-wave of the electroretinogram: applications and methods.
Hood DC, Birch DG
Doc Ophthalmol 1996-1997;92(4):253-67. doi: 10.1007/BF02584080. PMID: 9476593

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