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Thyroid gland macrofollicular adenoma

MedGen UID:
90763
•Concept ID:
C0334329
•
Neoplastic Process
Synonyms: Colloid adenoma; Colloid Adenoma; colloid adenoma; Macrofollicular Adenoma; Macrofollicular adenoma; macrofollicular adenoma; macrofollicular adenoma (morphologic abnormality); Thyroid Gland Macrofollicular Adenoma; thyroid gland macrofollicular adenoma
SNOMED CT: Macrofollicular adenoma (26545006); Colloid adenoma (26545006)
 
Monarch Initiative: MONDO:0004558

Definition

A thyroid gland adenoma composed of large size follicles. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThyroid gland macrofollicular adenoma

Recent clinical studies

Etiology

Clinicopathological profile of papillary carcinoma of thyroid: A 10-year experience in a tertiary care institute in North Karnataka, India.
Rao R, Giriyan SS, Rangappa PK
Indian J Cancer 2017 Jul-Sep;54(3):514-518. doi: 10.4103/ijc.IJC_337_17. PMID: 29798949
Comparison of intraoperative cytology with frozen sections in the diagnosis of thyroid lesions.
Tworek JA, Giordano TJ, Michael CW
Am J Clin Pathol 1998 Oct;110(4):456-61. doi: 10.1093/ajcp/110.4.456. PMID: 9763031
MUC1 mucin gene, transcripts, and protein in adenomas and papillary carcinomas of the thyroid.
Bièche I, Ruffet E, Zweibaum A, Vildé F, Lidereau R, Franc B
Thyroid 1997 Oct;7(5):725-31. doi: 10.1089/thy.1997.7.725. PMID: 9349575
Nondiagnostic fine needle aspiration biopsy of the thyroid gland: a diagnostic dilemma.
MacDonald L, Yazdi HM
Acta Cytol 1996 May-Jun;40(3):423-8. doi: 10.1159/000333893. PMID: 8669173
Efficacy of sonographically guided biopsy of thyroid masses and cervical lymph nodes.
Boland GW, Lee MJ, Mueller PR, Mayo-Smith W, Dawson SL, Simeone JF
AJR Am J Roentgenol 1993 Nov;161(5):1053-6. doi: 10.2214/ajr.161.5.8273609. PMID: 8273609

Diagnosis

Macrofollicular Variant of Follicular Thyroid Carcinoma: A Rare Underappreciated Pitfall in the Diagnosis of Thyroid Carcinoma.
Bongiovanni M, Sykiotis GP, La Rosa S, Bisig B, Trimech M, Missiaglia E, Gremaud M, Salvatori Chappuis V, De Vito C, Sciarra A, Foulkes WD, Pusztaszeri M
Thyroid 2020 Jan;30(1):72-80. Epub 2019 Dec 30 doi: 10.1089/thy.2018.0607. PMID: 31701808
DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors.
Jacques C, Guillotin D, Fontaine JF, Franc B, Mirebeau-Prunier D, Fleury A, Malthiery Y, Savagner F
J Clin Endocrinol Metab 2013 May;98(5):E981-9. Epub 2013 Apr 8 doi: 10.1210/jc.2012-4006. PMID: 23569218
The many faces and mimics of papillary thyroid carcinoma.
Albores-Saavedra J, Wu J
Endocr Pathol 2006 Spring;17(1):1-18. doi: 10.1385/ep:17:1:1. PMID: 16760576
MUC1 mucin gene, transcripts, and protein in adenomas and papillary carcinomas of the thyroid.
Bièche I, Ruffet E, Zweibaum A, Vildé F, Lidereau R, Franc B
Thyroid 1997 Oct;7(5):725-31. doi: 10.1089/thy.1997.7.725. PMID: 9349575
Sonographic tissue characterisation in thyroid gland diagnosis. A correlation between sonography and histology.
Müller HW, Schröder S, Schneider C, Seifert G
Klin Wochenschr 1985 Aug 1;63(15):706-10. doi: 10.1007/BF01733114. PMID: 3900555

Prognosis

Clinicopathological profile of papillary carcinoma of thyroid: A 10-year experience in a tertiary care institute in North Karnataka, India.
Rao R, Giriyan SS, Rangappa PK
Indian J Cancer 2017 Jul-Sep;54(3):514-518. doi: 10.4103/ijc.IJC_337_17. PMID: 29798949
The many faces and mimics of papillary thyroid carcinoma.
Albores-Saavedra J, Wu J
Endocr Pathol 2006 Spring;17(1):1-18. doi: 10.1385/ep:17:1:1. PMID: 16760576
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Kusunoki T, Nishida S, Kimoto-Kinoshita S, Murata K, Satou T, Tomura T
Asian J Surg 2002 Oct;25(4):304-8. doi: 10.1016/S1015-9584(09)60196-2. PMID: 12471003
MUC1 mucin gene, transcripts, and protein in adenomas and papillary carcinomas of the thyroid.
Bièche I, Ruffet E, Zweibaum A, Vildé F, Lidereau R, Franc B
Thyroid 1997 Oct;7(5):725-31. doi: 10.1089/thy.1997.7.725. PMID: 9349575
Thyroid scintigram in familial medullary carcinoma of the thyroid gland.
Anderson RJ, Sizemore GW, Wahner HW, Carney JA
Clin Nucl Med 1978 Apr;3(4):147-51. doi: 10.1097/00003072-197804000-00008. PMID: 657681

Clinical prediction guides

Macrofollicular Variant of Follicular Thyroid Carcinoma: A Rare Underappreciated Pitfall in the Diagnosis of Thyroid Carcinoma.
Bongiovanni M, Sykiotis GP, La Rosa S, Bisig B, Trimech M, Missiaglia E, Gremaud M, Salvatori Chappuis V, De Vito C, Sciarra A, Foulkes WD, Pusztaszeri M
Thyroid 2020 Jan;30(1):72-80. Epub 2019 Dec 30 doi: 10.1089/thy.2018.0607. PMID: 31701808
Improving the diagnostic accuracy of thyroid follicular neoplasms: cytological features in fine-needle aspiration cytology.
Maruta J, Hashimoto H, Suehisa Y, Yamashita H, Noguchi S, Aratake Y, Ohno E, Kobayashi TK
Diagn Cytopathol 2011 Jan;39(1):28-34. doi: 10.1002/dc.21321. PMID: 20091899
Type IV collagen, type IV collagenase activity and ability of cell proliferation in human thyroid tumours.
Kusunoki T, Nishida S, Kimoto-Kinoshita S, Murata K, Satou T, Tomura T
Asian J Surg 2002 Oct;25(4):304-8. doi: 10.1016/S1015-9584(09)60196-2. PMID: 12471003
MUC1 mucin gene, transcripts, and protein in adenomas and papillary carcinomas of the thyroid.
Bièche I, Ruffet E, Zweibaum A, Vildé F, Lidereau R, Franc B
Thyroid 1997 Oct;7(5):725-31. doi: 10.1089/thy.1997.7.725. PMID: 9349575
Autonomously functioning (hot) nodule of the thyroid gland. A clinical and histopathologic study of 17 cases.
Mizukami Y, Michigishi T, Nonomura A, Yokoyama K, Noguchi M, Hashimoto T, Nakamura S, Ishizaki T
Am J Clin Pathol 1994 Jan;101(1):29-35. doi: 10.1093/ajcp/101.1.29. PMID: 8279452

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