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Multinodular Adrenal Hyperplasia

MedGen UID:
926241
•Concept ID:
C4288709
•
Congenital Abnormality

Definition

A subtype of adrenal hyperplasia, based on histopathologic features, in which there are multiple nodules. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultinodular Adrenal Hyperplasia

Professional guidelines

PubMed

A multicenter experience on the prevalence of ARMC5 mutations in patients with primary bilateral macronodular adrenal hyperplasia: from genetic characterization to clinical phenotype.
Albiger NM, Regazzo D, Rubin B, Ferrara AM, Rizzati S, Taschin E, Ceccato F, Arnaldi G, Pecori Giraldi F, Stigliano A, Cerquetti L, Grimaldi F, De Menis E, Boscaro M, Iacobone M, Occhi G, Scaroni C
Endocrine 2017 Mar;55(3):959-968. Epub 2016 Apr 19 doi: 10.1007/s12020-016-0956-z. PMID: 27094308

Recent clinical studies

Etiology

Usefulness of CT scan, MRI and radiocholesterol scintigraphy for adrenal imaging in Cushing's syndrome.
Lumachi F, Zucchetta P, Marzola MC, Bui F, Casarrubea G, Angelini F, Favia G
Nucl Med Commun 2002 May;23(5):469-73. doi: 10.1097/00006231-200205000-00007. PMID: 11973488
Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism.
Doppman JL, Chrousos GP, Papanicolaou DA, Stratakis CA, Alexander HR, Nieman LK
Radiology 2000 Sep;216(3):797-802. doi: 10.1148/radiology.216.3.r00au40797. PMID: 10966714

Diagnosis

Usefulness of CT scan, MRI and radiocholesterol scintigraphy for adrenal imaging in Cushing's syndrome.
Lumachi F, Zucchetta P, Marzola MC, Bui F, Casarrubea G, Angelini F, Favia G
Nucl Med Commun 2002 May;23(5):469-73. doi: 10.1097/00006231-200205000-00007. PMID: 11973488
Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism.
Doppman JL, Chrousos GP, Papanicolaou DA, Stratakis CA, Alexander HR, Nieman LK
Radiology 2000 Sep;216(3):797-802. doi: 10.1148/radiology.216.3.r00au40797. PMID: 10966714

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