Adult intestinal botulism

MedGen UID:: 927523
•Concept ID:: C4289991
•: Disease or Syndrome

Synonyms:	Adult Intestinal Botulism; adult intestinal botulism; adult intestinal colonisation botulism; Adult intestinal colonization botulism; adult intestinal colonization botulism; adult intestinal toxaemia botulism; Adult intestinal toxemia botulism; adult intestinal toxemia botulism; Adult intestinal toxin-mediated botulism; adult intestinal toxin-mediated botulism; Infant-like botulism; infant-like botulism; intestinal botulism of adults
SNOMED CT:	Adult intestinal botulism (1285577000)

Monarch Initiative:	MONDO:0015806
Orphanet:	ORPHA178487

Definition

A very rare form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis caused by botulinum neurotoxins (BoNTs), and is due to intestinal colonization by <i>Clostridium botulinum</i> leading to toxin-mediated infection with toxemia. [from ORDO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAdult intestinal botulism

Acquired neuromuscular junction disease
- Botulism
  - Adult intestinal botulism

Professional guidelines

PubMed

Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.

Rao AK, Sobel J, Chatham-Stephens K, Luquez C
MMWR Recomm Rep 2021 May 7;70(2):1-30. doi: 10.15585/mmwr.rr7002a1. PMID: 33956777 Free PMC Article

Medical treatment for botulism.

Chalk CH, Benstead TJ, Pound JD, Keezer MR
Cochrane Database Syst Rev 2019 Apr 17;4(4):CD008123. doi: 10.1002/14651858.CD008123.pub4. PMID: 30993666 Free PMC Article

Medical treatment for botulism.

Chalk CH, Benstead TJ, Keezer M
Cochrane Database Syst Rev 2014 Feb 20;(2):CD008123. doi: 10.1002/14651858.CD008123.pub3. PMID: 24558013

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