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Malignant essential hypertension

MedGen UID:
9866
•Concept ID:
C0024588
•
Disease or Syndrome
Synonyms: Accelerated essential hypertension; accelerated essential hypertension; Malignant Essential Hypertension; malignant essential hypertension
SNOMED CT: Malignant essential hypertension (78975002); Accelerated essential hypertension (78975002)
 
Monarch Initiative: MONDO:0001133

Definition

Essential hypertension with rapid progression to severe high blood pressure, papilledema, and renal failure. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Prospective measurement of glomerular filtration rate and effective renal plasma flow during treatment of malignant essential hypertension.
Ghose RR
Postgrad Med J 1984 Oct;60(708):662-4. doi: 10.1136/pgmj.60.708.662. PMID: 6494086Free PMC Article

Recent clinical studies

Etiology

Renal function in treated and untreated hypertension.
Rahn KH
J Hum Hypertens 1998 Sep;12(9):599-601. doi: 10.1038/sj.jhh.1000672. PMID: 9783487
Does non-malignant essential hypertension cause renal damage? A clinician's view.
Beevers DG, Lip GY
J Hum Hypertens 1996 Oct;10(10):695-9. PMID: 9004097
Urinary kallikrein excretion is low in malignant essential hypertension.
Hilme E, Herlitz H, Gyzander E, Hansson L
J Hypertens 1992 Aug;10(8):869-74. PMID: 1325521
Predisposing factors for the development of malignant essential hypertension.
Sesoko S, Akema N, Matsukawa T, Kaneko Y
Arch Intern Med 1987 Oct;147(10):1721-4. PMID: 3662703
Renal function as an indicator of prognosis in malignant essential hypertension.
Herlitz H, Gudbrandsson T, Hansson L
Scand J Urol Nephrol 1982;16(1):51-5. doi: 10.3109/00365598209179640. PMID: 7089493

Diagnosis

Autoantibodies against the angiotensin receptor (AT1) in patients with hypertension.
Fu ML, Herlitz H, Schulze W, Wallukat G, Micke P, Eftekhari P, Sjögren KG, Hjalmarson A, Müller-Esterl W, Hoebeke J
J Hypertens 2000 Jul;18(7):945-53. doi: 10.1097/00004872-200018070-00017. PMID: 10930193
Renal function as an indicator of prognosis in malignant essential hypertension.
Herlitz H, Gudbrandsson T, Hansson L
Scand J Urol Nephrol 1982;16(1):51-5. doi: 10.3109/00365598209179640. PMID: 7089493

Therapy

Renal function in treated and untreated hypertension.
Rahn KH
J Hum Hypertens 1998 Sep;12(9):599-601. doi: 10.1038/sj.jhh.1000672. PMID: 9783487
Does non-malignant essential hypertension cause renal damage? A clinician's view.
Beevers DG, Lip GY
J Hum Hypertens 1996 Oct;10(10):695-9. PMID: 9004097
Structural cardiovascular changes in essential hypertension. Studies on the effect of antihypertensive therapy.
Dahlöf B
Blood Press Suppl 1992;6:1-75. PMID: 1345261
Urinary kallikrein excretion is low in malignant essential hypertension.
Hilme E, Herlitz H, Gyzander E, Hansson L
J Hypertens 1992 Aug;10(8):869-74. PMID: 1325521
Predisposing factors for the development of malignant essential hypertension.
Sesoko S, Akema N, Matsukawa T, Kaneko Y
Arch Intern Med 1987 Oct;147(10):1721-4. PMID: 3662703

Prognosis

Renal function in treated and untreated hypertension.
Rahn KH
J Hum Hypertens 1998 Sep;12(9):599-601. doi: 10.1038/sj.jhh.1000672. PMID: 9783487
Clinical features of end-stage renal failure in patients with essential hypertension.
Oda H, Tanaka S, Satta H, Tokita Y, Takagi N, Ishii M
Nihon Jinzo Gakkai Shi 1994 Apr;36(4):382-8. PMID: 8022111
Renal function as an indicator of prognosis in malignant essential hypertension.
Herlitz H, Gudbrandsson T, Hansson L
Scand J Urol Nephrol 1982;16(1):51-5. doi: 10.3109/00365598209179640. PMID: 7089493
An ultrastructural analysis of renal arterioles in benign and malignant essential hypertensions.
Mandal AK, Frohlich ED, Nordquist J
Ann Clin Lab Sci 1977 Mar-Apr;7(2):158-68. PMID: 851350

Clinical prediction guides

Human leukocyte antigens and malignant essential hypertension.
Gerbase-DeLima M, Paiva RL, Bortolotto LA, Bernardes-Silva H, De Lima JJ
Am J Hypertens 1998 Jun;11(6 Pt 1):729-31. doi: 10.1016/s0895-7061(98)00050-8. PMID: 9657633
Autoantibodies against cardiac G-protein-coupled receptors define different populations with cardiomyopathies but not with hypertension.
Fu ML, Hoebeke J, Matsui S, Matoba M, Magnusson Y, Hedner T, Herlitz H, Hjalmarson A
Clin Immunol Immunopathol 1994 Jul;72(1):15-20. doi: 10.1006/clin.1994.1101. PMID: 8020188
Renal haemodynamics and comparative effects of captopril in patients with benign- or malignant-essential hypertension, or with chronic renal failure.
Shionoiri H, Yasuda G, Takagi N, Oda H, Young SC, Miyajima E, Umemura S, Gotoh E, Sesoko S, Uneda S
Clin Exp Hypertens A 1987;9(2-3):543-9. doi: 10.3109/10641968709164222. PMID: 3301082
An ultrastructural analysis of renal arterioles in benign and malignant essential hypertensions.
Mandal AK, Frohlich ED, Nordquist J
Ann Clin Lab Sci 1977 Mar-Apr;7(2):158-68. PMID: 851350

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