From HPO
Hypercalciuria- MedGen UID:
- 43775
- •Concept ID:
- C0020438
- •
- Finding
Abnormally high level of calcium in the urine.
Nephrocalcinosis- MedGen UID:
- 10222
- •Concept ID:
- C0027709
- •
- Disease or Syndrome
Nephrocalcinosis is the deposition of calcium salts in renal parenchyma.
Glomerular sclerosis- MedGen UID:
- 61248
- •Concept ID:
- C0178664
- •
- Disease or Syndrome
Accumulation of scar tissue within the glomerulus.
Microscopic hematuria- MedGen UID:
- 65997
- •Concept ID:
- C0239937
- •
- Finding
Microscopic hematuria detected by dipstick or microscopic examination of the urine.
Nephrolithiasis- MedGen UID:
- 98227
- •Concept ID:
- C0392525
- •
- Disease or Syndrome
The presence of calculi (stones) in the kidneys.
Chronic kidney disease- MedGen UID:
- 473458
- •Concept ID:
- C1561643
- •
- Disease or Syndrome
Functional anomaly of the kidney persisting for at least three months.
Renal insufficiency- MedGen UID:
- 332529
- •Concept ID:
- C1565489
- •
- Disease or Syndrome
A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.
Proximal tubulopathy- MedGen UID:
- 326534
- •Concept ID:
- C1839603
- •
- Disease or Syndrome
Dysfunction of the proximal tubule, which is the portion of the duct system of the nephron of the kidney which leads from Bowman's capsule to the loop of Henle.
Low-molecular-weight proteinuria- MedGen UID:
- 333360
- •Concept ID:
- C1839606
- •
- Finding
Excretion in urine of proteins of a size smaller than albumin (molecular weight 69 kD).
Renal tubular atrophy- MedGen UID:
- 388054
- •Concept ID:
- C1858395
- •
- Finding
The presence of renal tubules with thick redundant basement membranes, or a reduction of greater than 50% in tubular diameter compared to surrounding non-atrophic tubules.
Tubulointerstitial fibrosis- MedGen UID:
- 370652
- •Concept ID:
- C1969372
- •
- Disease or Syndrome
A progressive detrimental connective tissue deposition (fibrosis) on the kidney parenchyma involving the tubules and interstitial tissue of the kidney. Tubulointerstitial injury in the kidney is complex, involving a number of independent and overlapping cellular and molecular pathways, with renal interstitial fibrosis and tubular atrophy (IF/TA) as the final common pathway. However, IF and TA are separable, as shown by the profound TA in renal artery stenosis, which characteristically has little or no fibrosis (or inflammation). For new annotations it is preferable to annotate to the specific HPO terms for Renal interstitial fibrosis and/or Renal tubular atrophy.
- Abnormality of the genitourinary system