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Sleep myoclonus

MedGen UID:
155544
•Concept ID:
C0751352
•
Sign or Symptom
Synonyms: Myoclonus, Nocturnal; Myoclonus, Sleep; Nocturnal Myoclonus; Sleep Myoclonus
 
HPO: HP:0012323

Definition

Myoclonus that occurs during the initial phases of sleep. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Sleep myoclonus

Professional guidelines

PubMed

Differential diagnosis of epileptic seizures in infancy including the neonatal period.
Cross JH
Semin Fetal Neonatal Med 2013 Aug;18(4):192-5. Epub 2013 Apr 30 doi: 10.1016/j.siny.2013.04.003. PMID: 23642846
Treatment of sleep disturbances in depressed patients.
Neylan TC
J Clin Psychiatry 1995;56 Suppl 2:56-61. PMID: 7844108

Recent clinical studies

Etiology

Transient benign paroxysmal movement disorders in infancy.
Mosca S, Martins J, Temudo T
Rev Neurol 2022 Feb 16;74(4):135-140. doi: 10.33588/rn.7404.2021326. PMID: 35148422
Transient benign paroxysmal movement disorders in infancy.
Fernández-Alvarez E
Eur J Paediatr Neurol 2018 Mar;22(2):230-237. Epub 2018 Jan 12 doi: 10.1016/j.ejpn.2018.01.003. PMID: 29366536
Paroxysmal nonepileptic events in children with epilepsy.
Ito Y, Kidokoro H, Negoro T, Tanaka M, Okai Y, Sakaguchi Y, Ogawa C, Takeuchi T, Ohno A, Yamamoto H, Nakata T, Maesawa S, Watanabe K, Takahashi Y, Natsume J
Epilepsy Res 2017 May;132:59-63. Epub 2017 Feb 27 doi: 10.1016/j.eplepsyres.2017.02.009. PMID: 28315806
Synkinetic blepharoclonus.
Jacome DE
J Neuroophthalmol 2000 Dec;20(4):276-84. PMID: 11130758
Myoclonus and epilepsies.
Fejerman N
Indian J Pediatr 1997 Sep-Oct;64(5):583-602. doi: 10.1007/BF02726110. PMID: 10771893

Diagnosis

Childhood Neurologic Conditions: Movement Disorders.
Youssef P
FP Essent 2022 Dec;523:20-26. PMID: 36459665
Transient benign paroxysmal movement disorders in infancy.
Mosca S, Martins J, Temudo T
Rev Neurol 2022 Feb 16;74(4):135-140. doi: 10.33588/rn.7404.2021326. PMID: 35148422
Paroxysmal non-epileptic events in infancy: five cases with typical features.
Nagy E, Hollody K
Epileptic Disord 2019 Oct 1;21(5):458-462. doi: 10.1684/epd.2019.1098. PMID: 31649006
Synkinetic blepharoclonus.
Jacome DE
J Neuroophthalmol 2000 Dec;20(4):276-84. PMID: 11130758
Myoclonus and epilepsies.
Fejerman N
Indian J Pediatr 1997 Sep-Oct;64(5):583-602. doi: 10.1007/BF02726110. PMID: 10771893

Therapy

Benign neonatal sleep myoclonus: our experience of 15 Japanese cases.
Suzuki Y, Toshikawa H, Kimizu T, Kimura S, Ikeda T, Mogami Y, Yanagihara K
Brain Dev 2015 Jan;37(1):71-5. Epub 2014 Apr 18 doi: 10.1016/j.braindev.2014.03.010. PMID: 24750849
Benign neonatal sleep myoclonus: history and semiology.
Kaddurah AK, Holmes GL
Pediatr Neurol 2009 May;40(5):343-6. doi: 10.1016/j.pediatrneurol.2008.11.011. PMID: 19380069
Benign neonatal sleep myoclonus in newborn infants of opioid dependent mothers.
Held-Egli K, Rüegger C, Das-Kundu S, Schmitt B, Bucher HU
Acta Paediatr 2009 Jan;98(1):69-73. Epub 2008 Sep 17 doi: 10.1111/j.1651-2227.2008.01010.x. PMID: 18803624
Employing mirtazapine to aid benzodiazepine withdrawal.
Chandrasekaran PK
Singapore Med J 2008 Jun;49(6):e166-7. PMID: 18581012
Benign neonatal sleep myoclonus mimicking status epilepticus.
Turanli G, Senbil N, Altunbaşak S, Topçu M
J Child Neurol 2004 Jan;19(1):62-3. doi: 10.1177/08830738040190010708. PMID: 15032388

Prognosis

Benign neonatal sleep myoclonus: our experience of 15 Japanese cases.
Suzuki Y, Toshikawa H, Kimizu T, Kimura S, Ikeda T, Mogami Y, Yanagihara K
Brain Dev 2015 Jan;37(1):71-5. Epub 2014 Apr 18 doi: 10.1016/j.braindev.2014.03.010. PMID: 24750849
Differential diagnosis of epileptic seizures in infancy including the neonatal period.
Cross JH
Semin Fetal Neonatal Med 2013 Aug;18(4):192-5. Epub 2013 Apr 30 doi: 10.1016/j.siny.2013.04.003. PMID: 23642846
Benign neonatal sleep myoclonus: a review of the literature.
Maurer VO, Rizzi M, Bianchetti MG, Ramelli GP
Pediatrics 2010 Apr;125(4):e919-24. Epub 2010 Mar 29 doi: 10.1542/peds.2009-1839. PMID: 20351003
Clinical identification of the simple sleep-related movement disorders.
Walters AS
Chest 2007 Apr;131(4):1260-6. doi: 10.1378/chest.06-1602. PMID: 17426241
Myoclonus and epilepsies.
Fejerman N
Indian J Pediatr 1997 Sep-Oct;64(5):583-602. doi: 10.1007/BF02726110. PMID: 10771893

Clinical prediction guides

Paroxysmal nonepileptic events in children with epilepsy.
Ito Y, Kidokoro H, Negoro T, Tanaka M, Okai Y, Sakaguchi Y, Ogawa C, Takeuchi T, Ohno A, Yamamoto H, Nakata T, Maesawa S, Watanabe K, Takahashi Y, Natsume J
Epilepsy Res 2017 May;132:59-63. Epub 2017 Feb 27 doi: 10.1016/j.eplepsyres.2017.02.009. PMID: 28315806
Benign neonatal sleep myoclonus: our experience of 15 Japanese cases.
Suzuki Y, Toshikawa H, Kimizu T, Kimura S, Ikeda T, Mogami Y, Yanagihara K
Brain Dev 2015 Jan;37(1):71-5. Epub 2014 Apr 18 doi: 10.1016/j.braindev.2014.03.010. PMID: 24750849
Benign convulsions in newborns and infants: occurrence, clinical course and prognosis.
Hrastovec A, Hostnik T, Neubauer D
Eur J Paediatr Neurol 2012 Jan;16(1):64-73. Epub 2011 Nov 23 doi: 10.1016/j.ejpn.2011.10.006. PMID: 22116015
Benign neonatal sleep myoclonus: history and semiology.
Kaddurah AK, Holmes GL
Pediatr Neurol 2009 May;40(5):343-6. doi: 10.1016/j.pediatrneurol.2008.11.011. PMID: 19380069
Periodic leg movements during sleep and sleep disturbances in elders.
Youngstedt SD, Kripke DF, Klauber MR, Sepulveda RS, Mason WJ
J Gerontol A Biol Sci Med Sci 1998 Sep;53(5):M391-4. doi: 10.1093/gerona/53a.5.m391. PMID: 9754146

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