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Inflammatory bowel disease 13(IBD13)

MedGen UID:
394202
•Concept ID:
C2677101
•
Disease or Syndrome
Synonyms: IBD13; Inflammatory bowel disease 13, susceptibility to
 
Gene (location): ABCB1 (7q21.12)
 
Monarch Initiative: MONDO:0012831
OMIM®: 612244

Definition

Any inflammatory bowel disease in which the cause of the disease is a mutation in the ABCB1 gene. [from MONDO]

Clinical features

From HPO
Inflammation of the large intestine
MedGen UID:
662273
•Concept ID:
C0578878
•
Disease or Syndrome
Inflammation, or an inflammatory state in the large intestine.
See: Feature record | Search on this feature

Professional guidelines

PubMed

AGA Clinical Practice Update on Management of Iron Deficiency Anemia: Expert Review.
DeLoughery TG, Jackson CS, Ko CW, Rockey DC
Clin Gastroenterol Hepatol 2024 Aug;22(8):1575-1583. Epub 2024 Jun 12 doi: 10.1016/j.cgh.2024.03.046. PMID: 38864796
Nutritional Treatment in Crohn's Disease.
Caio G, Lungaro L, Caputo F, Zoli E, Giancola F, Chiarioni G, De Giorgio R, Zoli G
Nutrients 2021 May 12;13(5) doi: 10.3390/nu13051628. PMID: 34066229Free PMC Article
British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.
Lamb CA, Kennedy NA, Raine T, Hendy PA, Smith PJ, Limdi JK, Hayee B, Lomer MCE, Parkes GC, Selinger C, Barrett KJ, Davies RJ, Bennett C, Gittens S, Dunlop MG, Faiz O, Fraser A, Garrick V, Johnston PD, Parkes M, Sanderson J, Terry H; IBD guidelines eDelphi consensus group, Gaya DR, Iqbal TH, Taylor SA, Smith M, Brookes M, Hansen R, Hawthorne AB
Gut 2019 Dec;68(Suppl 3):s1-s106. Epub 2019 Sep 27 doi: 10.1136/gutjnl-2019-318484. PMID: 31562236Free PMC Article

Recent clinical studies

Etiology

A broad cuproptosis landscape in inflammatory bowel disease.
Chen Y, Li X, Sun R, Ji J, Yang F, Tian W, Ji W, Huang Q
Front Immunol 2022;13:1031539. Epub 2022 Nov 3 doi: 10.3389/fimmu.2022.1031539. PMID: 36405733Free PMC Article
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.
Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R
J Crohns Colitis 2022 May 10;16(4):633-642. doi: 10.1093/ecco-jcc/jjab191. PMID: 34739073
Dual Biologic or Small Molecule Therapy for Treatment of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
Ahmed W, Galati J, Kumar A, Christos PJ, Longman R, Lukin DJ, Scherl E, Battat R
Clin Gastroenterol Hepatol 2022 Mar;20(3):e361-e379. Epub 2021 Mar 31 doi: 10.1016/j.cgh.2021.03.034. PMID: 33798711
Enteric Viruses and Inflammatory Bowel Disease.
Tarris G, de Rougemont A, Charkaoui M, Michiels C, Martin L, Belliot G
Viruses 2021 Jan 13;13(1) doi: 10.3390/v13010104. PMID: 33451106Free PMC Article
Extraintestinal manifestations in inflammatory bowel disease - epidemiology, genetics, and pathogenesis.
Greuter T, Vavricka SR
Expert Rev Gastroenterol Hepatol 2019 Apr;13(4):307-317. Epub 2019 Feb 20 doi: 10.1080/17474124.2019.1574569. PMID: 30791773

Diagnosis

Immune-mediated inflammatory diseases and risk of venous thromboembolism: A Mendelian randomization study.
Lv X, Gao X, Liu J, Deng Y, Nie Q, Fan X, Ye Z, Liu P, Wen J
Front Immunol 2022;13:1042751. Epub 2022 Dec 13 doi: 10.3389/fimmu.2022.1042751. PMID: 36582224Free PMC Article
A broad cuproptosis landscape in inflammatory bowel disease.
Chen Y, Li X, Sun R, Ji J, Yang F, Tian W, Ji W, Huang Q
Front Immunol 2022;13:1031539. Epub 2022 Nov 3 doi: 10.3389/fimmu.2022.1031539. PMID: 36405733Free PMC Article
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.
Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R
J Crohns Colitis 2022 May 10;16(4):633-642. doi: 10.1093/ecco-jcc/jjab191. PMID: 34739073
Enteric Viruses and Inflammatory Bowel Disease.
Tarris G, de Rougemont A, Charkaoui M, Michiels C, Martin L, Belliot G
Viruses 2021 Jan 13;13(1) doi: 10.3390/v13010104. PMID: 33451106Free PMC Article
Role of intestinal microbiota and metabolites in inflammatory bowel disease.
Dong LN, Wang M, Guo J, Wang JP
Chin Med J (Engl) 2019 Jul 5;132(13):1610-1614. doi: 10.1097/CM9.0000000000000290. PMID: 31090547Free PMC Article

Therapy

Immune-mediated inflammatory diseases and risk of venous thromboembolism: A Mendelian randomization study.
Lv X, Gao X, Liu J, Deng Y, Nie Q, Fan X, Ye Z, Liu P, Wen J
Front Immunol 2022;13:1042751. Epub 2022 Dec 13 doi: 10.3389/fimmu.2022.1042751. PMID: 36582224Free PMC Article
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.
Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R
J Crohns Colitis 2022 May 10;16(4):633-642. doi: 10.1093/ecco-jcc/jjab191. PMID: 34739073
Dual Biologic or Small Molecule Therapy for Treatment of Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.
Ahmed W, Galati J, Kumar A, Christos PJ, Longman R, Lukin DJ, Scherl E, Battat R
Clin Gastroenterol Hepatol 2022 Mar;20(3):e361-e379. Epub 2021 Mar 31 doi: 10.1016/j.cgh.2021.03.034. PMID: 33798711
Diet-Microbiota Interactions in Inflammatory Bowel Disease.
Sugihara K, Kamada N
Nutrients 2021 May 1;13(5) doi: 10.3390/nu13051533. PMID: 34062869Free PMC Article
Extraintestinal manifestations in inflammatory bowel disease - epidemiology, genetics, and pathogenesis.
Greuter T, Vavricka SR
Expert Rev Gastroenterol Hepatol 2019 Apr;13(4):307-317. Epub 2019 Feb 20 doi: 10.1080/17474124.2019.1574569. PMID: 30791773

Prognosis

Incidence of Inflammatory Bowel Disease in Urban China: A Nationwide Population-based Study.
Xu L, He B, Sun Y, Li J, Shen P, Hu L, Liu G, Wang J, Duan L, Zhan S, Wang S
Clin Gastroenterol Hepatol 2023 Dec;21(13):3379-3386.e29. Epub 2023 Sep 1 doi: 10.1016/j.cgh.2023.08.013. PMID: 37660767
Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses.
Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JWY, Abreu MT, Rubin DT, Bernstein CN, Banerjee R, Yamamoto-Furusho JK, Panaccione R, Seow CH, Ma C, Underwood FE, Ahuja V, Panaccione N, Shaheen AA, Holroyd-Leduc J, Kaplan GG; Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) Research Group, Balderramo D, Chong VH, Juliao-Baños F, Dutta U, Simadibrata M, Kaibullayeva J, Sun Y, Hilmi I, Raja Ali RA, Paudel MS, Altuwaijri M, Hartono JL, Wei SC, Limsrivilai J, El Ouali S, Vergara BI, Dao VH, Kelly P, Hodges P, Miao Y, Li M
Clin Gastroenterol Hepatol 2023 Aug;21(9):2211-2221. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.06.030. PMID: 35863682
Immune-mediated inflammatory diseases and risk of venous thromboembolism: A Mendelian randomization study.
Lv X, Gao X, Liu J, Deng Y, Nie Q, Fan X, Ye Z, Liu P, Wen J
Front Immunol 2022;13:1042751. Epub 2022 Dec 13 doi: 10.3389/fimmu.2022.1042751. PMID: 36582224Free PMC Article
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.
Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R
J Crohns Colitis 2022 May 10;16(4):633-642. doi: 10.1093/ecco-jcc/jjab191. PMID: 34739073
Extraintestinal manifestations in inflammatory bowel disease - epidemiology, genetics, and pathogenesis.
Greuter T, Vavricka SR
Expert Rev Gastroenterol Hepatol 2019 Apr;13(4):307-317. Epub 2019 Feb 20 doi: 10.1080/17474124.2019.1574569. PMID: 30791773

Clinical prediction guides

Immune-mediated inflammatory diseases and risk of venous thromboembolism: A Mendelian randomization study.
Lv X, Gao X, Liu J, Deng Y, Nie Q, Fan X, Ye Z, Liu P, Wen J
Front Immunol 2022;13:1042751. Epub 2022 Dec 13 doi: 10.3389/fimmu.2022.1042751. PMID: 36582224Free PMC Article
A broad cuproptosis landscape in inflammatory bowel disease.
Chen Y, Li X, Sun R, Ji J, Yang F, Tian W, Ji W, Huang Q
Front Immunol 2022;13:1031539. Epub 2022 Nov 3 doi: 10.3389/fimmu.2022.1031539. PMID: 36405733Free PMC Article
Inflammatory Bowel Disease Treatments and Predictive Biomarkers of Therapeutic Response.
Elhag DA, Kumar M, Saadaoui M, Akobeng AK, Al-Mudahka F, Elawad M, Al Khodor S
Int J Mol Sci 2022 Jun 23;23(13) doi: 10.3390/ijms23136966. PMID: 35805965Free PMC Article
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study.
Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R
J Crohns Colitis 2022 May 10;16(4):633-642. doi: 10.1093/ecco-jcc/jjab191. PMID: 34739073
Extraintestinal manifestations in inflammatory bowel disease - epidemiology, genetics, and pathogenesis.
Greuter T, Vavricka SR
Expert Rev Gastroenterol Hepatol 2019 Apr;13(4):307-317. Epub 2019 Feb 20 doi: 10.1080/17474124.2019.1574569. PMID: 30791773

Recent systematic reviews

Global Hospitalization Trends for Crohn's Disease and Ulcerative Colitis in the 21st Century: A Systematic Review With Temporal Analyses.
Buie MJ, Quan J, Windsor JW, Coward S, Hansen TM, King JA, Kotze PG, Gearry RB, Ng SC, Mak JWY, Abreu MT, Rubin DT, Bernstein CN, Banerjee R, Yamamoto-Furusho JK, Panaccione R, Seow CH, Ma C, Underwood FE, Ahuja V, Panaccione N, Shaheen AA, Holroyd-Leduc J, Kaplan GG; Global IBD Visualization of Epidemiology Studies in the 21st Century (GIVES-21) Research Group, Balderramo D, Chong VH, Juliao-Baños F, Dutta U, Simadibrata M, Kaibullayeva J, Sun Y, Hilmi I, Raja Ali RA, Paudel MS, Altuwaijri M, Hartono JL, Wei SC, Limsrivilai J, El Ouali S, Vergara BI, Dao VH, Kelly P, Hodges P, Miao Y, Li M
Clin Gastroenterol Hepatol 2023 Aug;21(9):2211-2221. Epub 2022 Jul 19 doi: 10.1016/j.cgh.2022.06.030. PMID: 35863682
Comparative efficacy and safety of biologic therapies for moderate-to-severe Crohn's disease: a systematic review and network meta-analysis.
Singh S, Murad MH, Fumery M, Sedano R, Jairath V, Panaccione R, Sandborn WJ, Ma C
Lancet Gastroenterol Hepatol 2021 Dec;6(12):1002-1014. Epub 2021 Oct 22 doi: 10.1016/S2468-1253(21)00312-5. PMID: 34688373Free PMC Article
Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis.
Barberio B, Zamani M, Black CJ, Savarino EV, Ford AC
Lancet Gastroenterol Hepatol 2021 May;6(5):359-370. Epub 2021 Mar 12 doi: 10.1016/S2468-1253(21)00014-5. PMID: 33721557
STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD.
Turner D, Ricciuto A, Lewis A, D'Amico F, Dhaliwal J, Griffiths AM, Bettenworth D, Sandborn WJ, Sands BE, Reinisch W, Schölmerich J, Bemelman W, Danese S, Mary JY, Rubin D, Colombel JF, Peyrin-Biroulet L, Dotan I, Abreu MT, Dignass A; International Organization for the Study of IBD
Gastroenterology 2021 Apr;160(5):1570-1583. Epub 2021 Feb 19 doi: 10.1053/j.gastro.2020.12.031. PMID: 33359090
First- and Second-Line Pharmacotherapies for Patients With Moderate to Severely Active Ulcerative Colitis: An Updated Network Meta-Analysis.
Singh S, Murad MH, Fumery M, Dulai PS, Sandborn WJ
Clin Gastroenterol Hepatol 2020 Sep;18(10):2179-2191.e6. Epub 2020 Jan 13 doi: 10.1016/j.cgh.2020.01.008. PMID: 31945470Free PMC Article

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