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Neurodegeration

MedGen UID:
832957
•Concept ID:
CN228311
•
Finding

Recent clinical studies

Etiology

Exploring Radial Asymmetry in MR Diffusion Tensor Imaging and Its Impact on the Interpretation of Glymphatic Mechanisms.
Wright AM, Wu YC, Chen NK, Wen Q
J Magn Reson Imaging 2024 Oct;60(4):1432-1441. Epub 2023 Dec 29 doi: 10.1002/jmri.29203. PMID: 38156600Free PMC Article
The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions.
Brooks PJ
Free Radic Biol Med 2017 Jun;107:90-100. Epub 2016 Dec 21 doi: 10.1016/j.freeradbiomed.2016.12.028. PMID: 28011151
Mechanisms of neurodegeration in type 2 diabetes and the neuroprotective potential of dipeptidyl peptidase 4 inhibitors.
Matteucci E, Giampietro O
Curr Med Chem 2015;22(13):1573-81. doi: 10.2174/0929867322666150227153308. PMID: 25723507

Diagnosis

Tear biomarkers for Alzheimer's disease screening and diagnosis (the TearAD study): design and rationale of an observational longitudinal multicenter study.
van de Sande N, Ramakers IHGB, Visser PJ, Verhey FRJ, Verbraak FD, Bouwman FH, Berendschot TTJM, Nuijts RMMA, Webers CAB, Gijs M
BMC Neurol 2023 Aug 5;23(1):293. doi: 10.1186/s12883-023-03335-y. PMID: 37543602Free PMC Article
Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease.
Brooks PJ
DNA Repair (Amst) 2013 Aug;12(8):656-71. Epub 2013 May 16 doi: 10.1016/j.dnarep.2013.04.018. PMID: 23683874Free PMC Article

Therapy

Mechanisms of neurodegeration in type 2 diabetes and the neuroprotective potential of dipeptidyl peptidase 4 inhibitors.
Matteucci E, Giampietro O
Curr Med Chem 2015;22(13):1573-81. doi: 10.2174/0929867322666150227153308. PMID: 25723507
Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease.
Brooks PJ
DNA Repair (Amst) 2013 Aug;12(8):656-71. Epub 2013 May 16 doi: 10.1016/j.dnarep.2013.04.018. PMID: 23683874Free PMC Article
Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons.
Iwakura Y, Piao YS, Mizuno M, Takei N, Kakita A, Takahashi H, Nawa H
J Neurochem 2005 May;93(4):974-83. doi: 10.1111/j.1471-4159.2005.03073.x. PMID: 15857400
Bioremediation meets biomedicine: therapeutic translation of microbial catabolism to the lysosome.
de Grey AD
Trends Biotechnol 2002 Nov;20(11):452-5. doi: 10.1016/s0167-7799(02)02062-0. PMID: 12413818
Oxidative stress: free radical production in neural degeneration.
Götz ME, Künig G, Riederer P, Youdim MB
Pharmacol Ther 1994;63(1):37-122. doi: 10.1016/0163-7258(94)90055-8. PMID: 7972344

Clinical prediction guides

Exploring Radial Asymmetry in MR Diffusion Tensor Imaging and Its Impact on the Interpretation of Glymphatic Mechanisms.
Wright AM, Wu YC, Chen NK, Wen Q
J Magn Reson Imaging 2024 Oct;60(4):1432-1441. Epub 2023 Dec 29 doi: 10.1002/jmri.29203. PMID: 38156600Free PMC Article
Tear biomarkers for Alzheimer's disease screening and diagnosis (the TearAD study): design and rationale of an observational longitudinal multicenter study.
van de Sande N, Ramakers IHGB, Visser PJ, Verhey FRJ, Verbraak FD, Bouwman FH, Berendschot TTJM, Nuijts RMMA, Webers CAB, Gijs M
BMC Neurol 2023 Aug 5;23(1):293. doi: 10.1186/s12883-023-03335-y. PMID: 37543602Free PMC Article

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