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Pygmy

MedGen UID:
376605
•Concept ID:
C1849524
•
Disease or Syndrome
Synonym: PYGMY, AFRICAN
 
OMIM®: 265850

Clinical features

From HPO
Short stature
MedGen UID:
87607
•Concept ID:
C0349588
•
Finding
A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to "short stature" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms).
See: Feature record | Search on this feature
Abnormality of metabolism/homeostasis
MedGen UID:
867398
•Concept ID:
C4021768
•
Finding
See: Feature record | Search on this feature
Abnormality of the endocrine system
MedGen UID:
893021
•Concept ID:
C4025823
•
Anatomical Abnormality
An abnormality of the endocrine system.
See: Feature record | Search on this feature
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Professional guidelines

PubMed

Epidemiology and Genetic Variability of HHV-8/KSHV among Rural Populations and Kaposi's Sarcoma Patients in Gabon, Central Africa. Review of the Geographical Distribution of HHV-8 K1 Genotypes in Africa.
Mamimandjiami AI, Mouinga-Ondémé A, Ramassamy JL, Djuicy DD, Afonso PV, Mahé A, Lekana-Douki JB, Cassar O, Gessain A
Viruses 2021 Jan 25;13(2) doi: 10.3390/v13020175. PMID: 33503816Free PMC Article
Diagnosis and treatment of congestive heart failure secondary to dilated cardiomyopathy in a hedgehog.
Delk KW, Eshar D, Garcia E, Harkin K
J Small Anim Pract 2014 Mar;55(3):174-7. Epub 2013 Dec 23 doi: 10.1111/jsap.12169. PMID: 24372164
TT viruses (TTV) of non-human primates and their relationship to the human TTV genotypes.
Verschoor EJ, Langenhuijzen S, Heeney JL
J Gen Virol 1999 Sep;80 ( Pt 9):2491-2499. doi: 10.1099/0022-1317-80-9-2491. PMID: 10501506

Recent clinical studies

Therapy

The Natural History of a Pygmy Rattlesnake Bite.
Kostick N, O'Loughlin K
J Emerg Med 2021 Oct;61(4):e93-e95. Epub 2021 Jun 24 doi: 10.1016/j.jemermed.2021.04.021. PMID: 34175189
Tooth dimensions and body size in a Pygmy population.
Ramirez-Rozzi FV, Romero A
Ann Hum Biol 2019 Sep;46(6):467-474. Epub 2019 Oct 16 doi: 10.1080/03014460.2019.1673482. PMID: 31554436
From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs.
Lazarovici P, Marcinkiewicz C, Lelkes PI
Toxins (Basel) 2019 May 27;11(5) doi: 10.3390/toxins11050303. PMID: 31137917Free PMC Article
A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.
Bamford CGG, Aranday-Cortes E, Filipe IC, Sukumar S, Mair D, Filipe ADS, Mendoza JL, Garcia KC, Fan S, Tishkoff SA, McLauchlan J
PLoS Pathog 2018 Oct;14(10):e1007307. Epub 2018 Oct 11 doi: 10.1371/journal.ppat.1007307. PMID: 30308076Free PMC Article
Hazardous hedgehogs.
Rosen T
South Med J 2000 Sep;93(9):936-8. PMID: 11005362

Prognosis

Distribution and Numbers of Pygmies in Central African Forests.
Olivero J, Fa JE, Farfán MA, Lewis J, Hewlett B, Breuer T, Carpaneto GM, Fernández M, Germi F, Hattori S, Head J, Ichikawa M, Kitanaishi K, Knights J, Matsuura N, Migliano A, Nese B, Noss A, Ekoumou DO, Paulin P, Real R, Riddell M, Stevenson EG, Toda M, Vargas JM, Yasuoka H, Nasi R
PLoS One 2016;11(1):e0144499. Epub 2016 Jan 6 doi: 10.1371/journal.pone.0144499. PMID: 26735953Free PMC Article
Architecture and functional ecology of the human gastrocnemius muscle-tendon unit.
Butler EE, Dominy NJ
J Anat 2016 Apr;228(4):561-8. Epub 2015 Dec 29 doi: 10.1111/joa.12432. PMID: 26712532Free PMC Article
Health of Indigenous people in Africa.
Ohenjo N, Willis R, Jackson D, Nettleton C, Good K, Mugarura B
Lancet 2006 Jun 10;367(9526):1937-46. doi: 10.1016/S0140-6736(06)68849-1. PMID: 16765763
Hazardous hedgehogs.
Rosen T
South Med J 2000 Sep;93(9):936-8. PMID: 11005362
Pygmy locomotion.
Minetti AE, Saibene F, Ardigò LP, Atchou G, Schena F, Ferretti G
Eur J Appl Physiol Occup Physiol 1994;68(4):285-90. doi: 10.1007/BF00571444. PMID: 8055884

Clinical prediction guides

Population structure of pygmy (Kogia breviceps) and dwarf (Kogia sima) sperm whales in the Southern Hemisphere may reflect foraging ecology and dispersal patterns.
Plön S, Best PB, Duignan P, Lavery SD, Bernard RTF, Van Waerebeek K, Baker CS
Adv Mar Biol 2023;96:85-114. Epub 2023 Nov 10 doi: 10.1016/bs.amb.2023.09.001. PMID: 37980130
On the Bantu expansion.
Rowold DJ, Perez-Benedico D, Stojkovic O, Alfonso-Sanchez MA, Garcia-Bertrand R, Herrera RJ
Gene 2016 Nov 15;593(1):48-57. Epub 2016 Jul 19 doi: 10.1016/j.gene.2016.07.044. PMID: 27451076
Architecture and functional ecology of the human gastrocnemius muscle-tendon unit.
Butler EE, Dominy NJ
J Anat 2016 Apr;228(4):561-8. Epub 2015 Dec 29 doi: 10.1111/joa.12432. PMID: 26712532Free PMC Article
Indirect evidence for the genetic determination of short stature in African Pygmies.
Becker NS, Verdu P, Froment A, Le Bomin S, Pagezy H, Bahuchet S, Heyer E
Am J Phys Anthropol 2011 Jul;145(3):390-401. Epub 2011 May 3 doi: 10.1002/ajpa.21512. PMID: 21541921
Pygmy locomotion.
Minetti AE, Saibene F, Ardigò LP, Atchou G, Schena F, Ferretti G
Eur J Appl Physiol Occup Physiol 1994;68(4):285-90. doi: 10.1007/BF00571444. PMID: 8055884

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