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1.

Estrogen resistance syndrome

Estrogen resistance (ESTRR) is characterized by absence of puberty with elevated estradiol and gonadotropic hormones, as well as markedly delayed bone maturation. Female patients show absent breast development, small uterus, and enlarged multicystic ovaries; male patients may show small testes (Bernard et al., 2017). Some patients exhibit continued growth into adulthood (Smith et al., 1994). [from OMIM]

MedGen UID:
815580
Concept ID:
C3809250
Disease or Syndrome
2.

Increased serum estradiol

An elevation above normal limits of the concentration of estradiol in the circulation. [from HPO]

MedGen UID:
717742
Concept ID:
C1295643
Finding

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