Poliomyelitis
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)
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Tree Number(s): C01.207.618.750, C01.925.782.687.359.764, C10.228.228.618.750, C10.228.854.525.850, C10.586.750.850, C10.668.864
MeSH Unique ID: D011051
Entry Terms:
- Poliomyelitis Infection
- Infection, Poliomyelitis
- Infections, Poliomyelitis
- Poliomyelitis Infections
- Polio
- Polios
- Epidemic Acute Poliomyelitis
- Acute Poliomyelitis, Epidemic
- Poliomyelitis, Epidemic Acute
- Poliomyelitis, Acute
- Acute Poliomyelitis
- Infantile Paralysis
- Paralysis, Infantile
- Poliomyelitis, Nonpoliovirus
- Nonpoliovirus Poliomyelitis
- Poliomyelitis, Preparalytic
- Poliomyelitides, Preparalytic
- Preparalytic Poliomyelitis
- Encephalitis, Polio
- Polio Encephalitis
See Also: