RNA 5' Terminal Oligopyrimidine Sequence
A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
Year introduced: 2003
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Subheadings:
Tree Number(s): G02.111.570.080.689.687.275, G05.360.080.689.687.275, G05.360.340.024.340.137.785
MeSH Unique ID: D038641
Entry Terms:
- RNA 5' Terminal Oligopyrimidine Regulatory Sequence
- 5' TOP Sequence
- 5' TOP Sequences
- Sequence, 5' TOP
- Sequences, 5' TOP
- 5' TOP mRNA
- 5' TOP Messenger RNA