DNA Sequence, Unstable

A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.

Year introduced: 2004 (1998)

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Tree Number(s): G05.360.340.024.189

MeSH Unique ID: D043243

Entry Terms:

• DNA Sequences, Unstable
• Sequences, Unstable DNA
• Sequence, Unstable DNA
• Unstable DNA Sequence
• Unstable DNA Sequences

See Also:

• Chromosome Fragility
• Genomic Instability

All MeSH Categories
Phenomena and Processes Category
Genetic Phenomena
Genetic Structures
Genome
Genome Components
DNA Sequence, Unstable
Chromosome Fragile Sites
DNA Repeat Expansion
Trinucleotide Repeat Expansion