Claudin-1

An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.

Year introduced: 2013

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Tree Number(s): D12.776.543.940.200.100

MeSH Unique ID: D062445

Entry Terms:

• Claudin 1

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Membrane Proteins
Tight Junction Proteins
Claudins
Claudin-1