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DNA Topoisomerases, Type I

DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.

Year introduced: 2002

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Subheadings:

Tree Number(s): D08.811.399.403.483, D12.776.157.687.375, D12.776.660.720.375

MeSH Unique ID: D004264

Registry Number: EC 5.99.1.2

Entry Terms:

  • DNA Nicking-Closing Proteins
  • DNA Nicking-Closing Protein
  • DNA Relaxing Enzymes
  • DNA Relaxing Enzyme
  • DNA Relaxing Protein
  • DNA Topoisomerase
  • DNA Untwisting Enzyme
  • DNA Type 1 Topoisomerase
  • DNA Untwisting Enzymes
  • DNA Untwisting Proteins
  • DNA Untwisting Protein
  • Topoisomerase I
  • Type I DNA Topoisomerase
  • DNA Topoisomerase I
  • DNA Topoisomerase III alpha
  • TOP3alpha
  • TOPO IIIalpha
  • IIIalpha, TOPO
  • Topoisomerase IIIalpha
  • IIIalpha, Topoisomerase
  • DNA Topoisomerase III beta
  • Topoisomerase III beta
  • beta, Topoisomerase III
  • III beta, Topoisomerase
  • Topoisomerase IIIbeta
  • IIIbeta, Topoisomerase
  • DNA Topoisomerase III
  • III, DNA Topoisomerase
  • Topoisomerase III, DNA
  • Topo III
  • III, Topo
  • Topoisomerase III
  • III, Topoisomerase
  • TOP3 Topoisomerase
  • Topoisomerase, TOP3

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