Proteasome Endopeptidase Complex
A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
Year introduced: 2005
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Subheadings:
Tree Number(s): D05.500.562.500, D08.811.277.656.918, D08.811.600.730
MeSH Unique ID: D046988
Registry Number: EC 3.4.25.1
Entry Terms:
- Complex, Proteasome Endopeptidase
- Endopeptidase Complex, Proteasome
- Macroxyproteinase
- Multicatalytic Endopeptidase Complex
- Complex, Multicatalytic Endopeptidase
- Endopeptidase Complex, Multicatalytic
- Multicatalytic Proteinase
- Proteinase, Multicatalytic
- Prosome
- Proteasome
- Macropain
- 20S Proteasome
- Proteasome, 20S
- Ingensin
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