Addison Disease
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
Year introduced: 2005 (1963)
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Subheadings:
Tree Number(s): C19.053.500.263, C20.111.163
MeSH Unique ID: D000224
Entry Terms:
- Disease, Addison
- Addison's Disease
- Addisons Disease
- Primary Adrenal Insufficiency
- Adrenal Insufficiency, Primary
- Primary Adrenocortical Insufficiency
- Adrenocortical Insufficiencies, Primary
- Adrenocortical Insufficiency, Primary
- Insufficiencies, Primary Adrenocortical
- Insufficiency, Primary Adrenocortical
- Primary Adrenocortical Insufficiencies
- Primary Hypoadrenalism
- Hypoadrenalism, Primary
- Hypoadrenalisms, Primary