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4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid [Supplementary Concept]
a potent and specific inhibitor of p300/CBP HAT activity
Date introduced: November 22, 2013
Pyrazolones
Compounds with a five-membered heterocyclic ring with two nitrogens and a keto OXYGEN. Some are inhibitors of TNF-ALPHA production.
Year introduced: 2005
Pyrazoles
Azoles of two nitrogens at the 1,2 positions, next to each other, in contrast with IMIDAZOLES in which they are at the 1,3 positions.
Organic Chemicals
A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.
Year introduced: 1998
Nitrobenzenes
BENZENE derivatives carrying nitro group substituents.
Nitro Compounds
Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES.
Year introduced: 1974(1971)
Hydrocarbons, Cyclic
Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.
Hydrocarbons, Aromatic
Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
Hydrocarbons
Organic compounds that primarily contain carbon and hydrogen atoms with the carbon atoms forming a linear or circular structure.
Heterocyclic Compounds, 1-Ring
Organic compounds that contain a ring structure made up of carbon and one or more additional elements such as nitrogen and oxygen.
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Carboxylic Acids
Organic compounds containing the carboxy group (-COOH). This group of compounds includes amino acids and fatty acids. Carboxylic acids can be saturated, unsaturated, or aromatic.
Year introduced: 1973(1971)
Benzoates
Derivatives of BENZOIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxybenzene structure.
Year introduced: 1963
Benzene Derivatives
Organic compounds derived from BENZENE.
Year introduced: 1968
Azoles
Five membered rings containing a NITROGEN atom.
Acids, Carbocyclic
Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon.