MeSH

A pyrazine and boronic acid derivative that functions as a reversible PROTEASOME INHIBITOR. It is used as an ANTINEOPLASTIC AGENT in the treatment of MULTIPLE MYELOMA and MANTLE CELL LYMPHOMA.

Year introduced: 2016 (2000)

Substances that inhibit or prevent the proliferation of NEOPLASMS.

A heterocyclic aromatic organic compound with the chemical formula C4H4N2.

A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.

Year introduced: 1998

A broad class of substances encompassing all those that do not include carbon and its derivatives as their principal elements. However, carbides, carbonates, cyanides, cyanates, and carbon disulfide are included in this class.

Year introduced: 1998

Organic compounds that contain a ring structure made up of carbon and one or more additional elements such as nitrogen and oxygen.

Year introduced: 1998

Cyclic compounds that include atoms other than carbon in their ring structure.

Inorganic or organic compounds that contain the basic structure RB(OH)2.

Year introduced: 1968

Inorganic or organic compounds that contain boron as an integral part of the molecule.

Year introduced: 1968

Inorganic acids with a non metal, other than carbon, attached to hydrogen, or an acid radical containing no carbon.

Year introduced: 1998

Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant and Hackh's Chemical Dictionary, 5th ed)

Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.

Year introduced: 2004

A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.

Year introduced: 2004(1999)

A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.

Year introduced: 1999