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leucyl-leucine-methyl ester [Supplementary Concept]
RN given refers to all L-isomer
Date introduced: May 31, 1985
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Year introduced: 1966(1964)
Peptides
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS.
Oligopeptides
Peptides composed of between two and twelve amino acids.
Year introduced: 1973
Dipeptides
Peptides composed of two amino acid units.
Amino Acids, Peptides, and Proteins
Amino acids and chains of amino acids connected by peptide linkages.
Year introduced: 1998
Physiological Effects of Drugs
Activities which affect organs and systemic functions without regard to a particular disease.
Year introduced: 2004
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999
Immunologic Factors
Biologically active substances whose activities affect or play a role in the functioning of the immune system.