Homo sapiens putative T7-like mitochondrial DNA helicase (C10orf2) mRN - Nucleotide

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Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7. [Mol Oncol. 2024]
Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Baxter JS, Brough R, Krastev DB, Song F, Sridhar S, Gulati A, Alexander J, Roumeliotis TI, Kozik Z, Choudhary JS, et al. Mol Oncol. 2024 Feb; 18(2):369-385. Epub 2023 Oct 22.
The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ. [J Biol Chem. 2023]
The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ.
Johnson LC, Singh A, Patel SS. J Biol Chem. 2023 Jan; 299(1):102797. Epub 2022 Dec 14.
Structural insight and characterization of human Twinkle helicase in mitochondrial disease. [Proc Natl Acad Sci U S A. 2022]
Structural insight and characterization of human Twinkle helicase in mitochondrial disease.
Riccio AA, Bouvette J, Perera L, Longley MJ, Krahn JM, Williams JG, Dutcher R, Borgnia MJ, Copeland WC. Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32):e2207459119. Epub 2022 Aug 1.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the TWNK gene.

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Nucleotide