A homozygous truncating mutation of FGL2 is associated with immune dysregulation.
Janssen E, Alosaimi MF, Alazami AM, Alsuliman A, Alaiya A, Al-Saud B, Al-Mousa H, Al-Zaid TJ, Smith E, Platt CD, et al. J Allergy Clin Immunol. 2023 Feb; 151(2):572-578.e1. Epub 2022 Oct 13.