Homo sapiens chromosome 21 open reading frame 2, mRNA (cDNA clone MGC: - Nucleotide

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The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body. [Open Biol. 2024]
The C-terminus of CFAP410 forms a tetrameric helical bundle that is essential for its localization to the basal body.
Stadler A, De Liz LV, Gabriel HB, Alonso-Gil S, Crickley R, Korbula K, Žagrović B, Vaughan S, Sunter JD, Dong G. Open Biol. 2024 Sep; 14(9):240128. Epub 2024 Sep 11.
ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons. [Acta Neuropathol Commun. 2024]
ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.
Zelina P, de Ruiter AA, Kolsteeg C, van Ginneken I, Vos HR, Supiot LF, Burgering BMT, Meye FJ, Veldink JH, van den Berg LH, et al. Acta Neuropathol Commun. 2024 Sep 4; 12(1):144. Epub 2024 Sep 4.
Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases. [Life Sci Alliance. 2023]
Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases.
Gregorczyk M, Pastore G, Muñoz I, Carroll T, Streubel J, Munro M, Lis P, Lange S, Lamoliatte F, Macartney T, et al. Life Sci Alliance. 2023 Jul; 6(7). Epub 2023 May 15.

RefSeq alternative splicing
See 22 reference mRNA sequence splice variants for the CFAP410 gene.

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Nucleotide