Homo sapiens complement C2 (C2), transcript variant 4, mRNA

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Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. [Diabetologia. 2023]
Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study.
Steffen BT, Tang W, Lutsey PL, Demmer RT, Selvin E, Matsushita K, Morrison AC, Guan W, Rooney MR, Norby FL, et al. Diabetologia. 2023 Jan; 66(1):105-115. Epub 2022 Oct 4.
Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein. [Front Immunol. 2021]
Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein.
Urban A, Kowalska D, Stasiłojć G, Kuźniewska A, Skrobińska A, Arjona E, Alonso EC, Fenollosa Segarra MÁ, Jongerius I, Spaapen R, et al. Front Immunol. 2021; 12:724361. Epub 2021 Nov 25.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. [Cell. 2021]
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Huttlin EL, Bruckner RJ, Navarrete-Perea J, Cannon JR, Baltier K, Gebreab F, Gygi MP, Thornock A, Zarraga G, Tam S, et al. Cell. 2021 May 27; 184(11):3022-3040.e28. Epub 2021 May 6.

RefSeq alternative splicing
See 6 reference mRNA sequence splice variants for the C2 gene.
RefSeq protein product
See the reference protein sequence for complement C2 isoform 4 (NP_001269386.1).

Protein
Protein sequence from Nucleotide coding region
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Functional Class
Functional class of the sequence domain architecture
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OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
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PubMed (Weighted)
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Nucleotide