Mus musculus NIMA (never in mitosis gene a)-related expressed kinase 8 - Nucleotide

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Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease. [Kidney Int. 2023]
Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease.
Claus LR, Chen C, Stallworth J, Turner JL, Slaats GG, Hawks AL, Mabillard H, Senum SR, Srikanth S, Flanagan-Steet H, et al. Kidney Int. 2023 Nov; 104(5):995-1007. Epub 2023 Aug 19.
Caspase-1 and the inflammasome promote polycystic kidney disease progression. [Front Mol Biosci. 2022]
Caspase-1 and the inflammasome promote polycystic kidney disease progression.
Swenson-Fields KI, Ward CJ, Lopez ME, Fross S, Heimes Dillon AL, Meisenheimer JD, Rabbani AJ, Wedlock E, Basu MK, Jansson KP, et al. Front Mol Biosci. 2022; 9:971219. Epub 2022 Nov 29.
Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease. [Lab Invest. 2020]
Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease.
Zhang JQJ, Burgess J, Stepanova D, Saravanabavan S, Wong ATY, Kaldis P, Rangan GK. Lab Invest. 2020 May; 100(5):696-711. Epub 2020 Jan 8.

RefSeq alternative splicing
See 4 reference mRNA sequence splice variants for the Nek8 gene.
RefSeq protein product
See the reference protein sequence for serine/threonine-protein kinase Nek8 (NP_543125.1).

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NIMA related kinase 8 [Guide to Pharmacology]
NIMA related kinase 8
Guide to Pharmacology
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Nucleotide