PREDICTED: Homo sapiens DNA topoisomerase III alpha (TOP3A), transcrip - Nucleotide

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Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7. [Mol Oncol. 2024]
Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Baxter JS, Brough R, Krastev DB, Song F, Sridhar S, Gulati A, Alexander J, Roumeliotis TI, Kozik Z, Choudhary JS, et al. Mol Oncol. 2024 Feb; 18(2):369-385. Epub 2023 Oct 22.
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability. [EMBO Mol Med. 2023]
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability.
Erdinc D, Rodríguez-Luis A, Fassad MR, Mackenzie S, Watson CM, Valenzuela S, Xie X, Menger KE, Sergeant K, Craig K, et al. EMBO Mol Med. 2023 May 8; 15(5):e16775. Epub 2023 Apr 4.
Chronic progressive external ophthalmoplegia plus syndrome due to homozygous missense variant in TOP3A gene. [Clin Genet. 2023]
Chronic progressive external ophthalmoplegia plus syndrome due to homozygous missense variant in TOP3A gene.
Llauradó A, Rovira-Moreno E, Codina-Solà M, Martínez-Saez E, Salvadó M, Sanchez-Tejerina D, Sotoca J, López-Diego V, Restrepo-Vera JL, Garcia-Arumi E, et al. Clin Genet. 2023 Apr; 103(4):492-494. Epub 2022 Dec 28.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the TOP3A gene.
RefSeq protein product
See the reference protein sequence for DNA topoisomerase 3-alpha isoform X2 (XP_054188090.1).

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Nucleotide