txid2731360[Organism:exp] - PubChem BioAssay - NCBI

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Select item 19599181.

Antiviral activity against Cytomegalovirus

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1959918

Summary Compounds, Active PubMed Citation

Select item 19566482.

Antiviral activity against HSV-1 KOS infected in human HEL 299 cells assessed as inhibition of virus-induced cytopathogenic effect incubated for 3 to 7 days by MTS assay

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 11 Tested

AID:: 1956648

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19550503.

Inhibition of HCMV DNA polymerase incubated for 10 mins in presence of dNTP by fluorescence based assay

Source:: ChEMBL

Assay data:11 Active, 7 Activity ≤ 1 µM, 11 Tested

AID:: 1955050

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19550454.

Antiviral activity against HCMV US3-6-EGFP-HCMV-AD169 infected in MRC5 cells assessed as inhibition of viral cytopathic effect incubated for 4 days by fluorescence based HTS assay

Source:: ChEMBL

Assay data:14 Active, 9 Activity ≤ 1 µM, 16 Tested

AID:: 1955045

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 19538235.

Antiviral activity against Herpes simplex virus 1 assessed as inhibition rate at 2.5 ug/ml relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1953823

Summary PubMed Citation

Select item 19538226.

Antiviral activity against Herpes simplex virus 1 assessed as inhibition rate at 5 ug/ml relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1953822

Summary PubMed Citation

Select item 19538217.

Antiviral activity against Herpes simplex virus 1 assessed as inhibition rate at 10 ug/ml relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1953821

Summary PubMed Citation

Select item 19538208.

Antiviral activity against Kaposi's sarcoma-associated herpesvirus

Source:: ChEMBL

Assay data:1 Active, 1 Tested

AID:: 1953820

Summary Compounds, Active PubMed Citation

Select item 19538199.

Antiviral activity against Herpes simplex virus 2

Source:: ChEMBL

Assay data:1 Tested

AID:: 1953819

Summary PubMed Citation

Select item 195380910.

Antiviral activity against Herpes simplex virus 1

Source:: ChEMBL

Assay data:5 Tested

AID:: 1953809

Summary PubMed Citation

Select item 195380811.

Antiviral activity against Herpes simplex virus 1 assessed as reduction in number of plaques at 0.12 mg/ml relative to control

Source:: ChEMBL

Assay data:1 Tested

AID:: 1953808

Summary PubMed Citation

Select item 195169112.

Antiviral activity against Human betaherpesvirus 5

Source:: ChEMBL

Assay data:2 Active, 2 Tested

AID:: 1951691

Summary Compounds, Active PubMed Citation

Select item 195168313.

Antiviral activity against Human betaherpesvirus 5 AD 169 infected in HFF cells

Source:: ChEMBL

Assay data:1 Active, 2 Tested

AID:: 1951683

Summary Compounds, Active PubMed Citation

Select item 194695014.

Antiviral activity against thymidine kinase deficient VZV 07-1 infected in HELF cells assessed as reduction in viral replication

Source:: ChEMBL

Assay data:1 Active, 7 Tested

AID:: 1946950

Summary Compounds, Active PubMed Citation

Select item 194694915.

Antiviral activity against thymidine kinase positive VZV OKA infected in HELF cells assessed as reduction in viral replication

Source:: ChEMBL

Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested

AID:: 1946949

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194694816.

Antiviral activity against HCMV Davis infected in HELF cells assessed as reduction in viral replication

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested

AID:: 1946948

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194694717.

Antiviral activity against HCMV AD-169 infected in HELF cells assessed as reduction in viral replication

Source:: ChEMBL

Assay data:2 Active, 7 Tested

AID:: 1946947

Summary Compounds, Active PubMed Citation

Select item 194326618.

Antiviral activity against HCMV

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1943266

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 194266319.

Potency index, ratio of ganciclovir IC50 to test compound IC50 for antiviral activity against Cytomegalovirus

Source:: ChEMBL

Assay data:1 Tested

AID:: 1942663

Summary PubMed Citation

Select item 194266220.

Potency index, ratio of test compound IC50 to ganciclovir IC50 for antiviral activity against Cytomegalovirus

Source:: ChEMBL

Assay data:1 Tested

AID:: 1942662

Summary PubMed Citation

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Target

Proteins (111)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,946)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (53)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (970)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (5)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (2,021)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (20)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (85)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (5,444)
BioAssays extracted from the literature
NIH MLP (87)
BioAssays deposited by the NIH Molecular Libraries Program
Other (4)
BioAssays deposited by other experimentalists

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