Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: Summary
Assay data:70 Active, 12 Activity ≤ 1 µM, 9667 Tested
Summary
p53 small molecule agonists, cell-based qHTS assay: Summary
Assay data:212 Active, 41 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Assay data:103 Active, 14 Activity ≤ 1 µM, 9667 Tested
p53 small molecule agonists, cell-based qHTS assay
Assay data:87 Active, 5 Activity ≤ 1 nM, 180 Activity ≤ 1 µM, 9667 Tested
Inhibitory Activity Assay from US Patent US20240109930: "TRIAZOLYL-METHYL SUBSTITUTED ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES"
Assay data:245 Active, 244 Activity ≤ 1 µM, 245 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
VEGFR ADP GLO Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:23 Active, 13 Activity ≤ 1 µM, 485 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
PDGFRβ LanthaScreen Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:478 Active, 11 Activity ≤ 1 nM, 468 Activity ≤ 1 µM, 485 Tested
PDGFRβ HTRF Assay from US Patent US20240109917: "PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS"
Assay data:485 Active, 377 Activity ≤ 1 nM, 483 Activity ≤ 1 µM, 485 Tested
Inhibition of the Activity of ACC1 from US Patent US20240109915: "NOVEL ACC INHIBITORS"
Assay data:99 Active, 1 Activity ≤ 1 nM, 99 Activity ≤ 1 µM, 101 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Mdm2-p53 Inhibition AlphaScreen Assay from US Patent US20240109913: "NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS"
Assay data:56 Active, 55 Activity ≤ 1 µM, 56 Tested
In Vitro CDK7 Assay from US Patent US20240109912: "TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS"
Assay data:135 Active, 110 Activity ≤ 1 nM, 131 Activity ≤ 1 µM, 135 Tested
SHP2 Inhibition Enzymatic Assay from US Patent US20240109900: "AZABICYCLIC SHP2 INHIBITORS"
Assay data:519 Active, 511 Activity ≤ 1 µM, 523 Tested
Activity Inhibition Assay on CDK Family Kinases from US Patent US20240109898: "SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVES, COMPOSITIONS AND PHARMACEUTICAL USES THEREOF"
Assay data:84 Active, 83 Activity ≤ 1 µM, 84 Tested
KRAS G12C-GDP Exchange Assay from US Patent US20240109893: "PREPARATION AND APPLICATION METHOD OF HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR"
Assay data:22 Active, 8 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 22 Tested
ADP-Glo Kinase Assay from US Patent US20240109890: "BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF"
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
KAT6A Biochemical Assay from US Patent US20240109880: "LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF"
Assay data:69 Active, 69 Activity ≤ 1 µM, 69 Tested
p300 and CBP Protein Activity Assay from US Patent US20240109879: "BENZIMIDAZOLE COMPOUND AND APPLICATION THEREOF"
Assay data:10 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Cereblon Binding Assay from US Patent US20240109877: "PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE"
Assay data:14 Active, 5 Activity ≤ 1 µM, 19 Tested
Electrophoretic Mobility Shift Assay (MSA) from US Patent US20240109877: "PYRIMIDINES FOR DEGRADING BRUTON'S TYROSINE KINASE"
Assay data:19 Active, 19 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
Kinase Assay from US Patent US20240109865: "INDAZOLE COMPOUNDS AS KINASE INHIBITORS"
Assay data:359 Active, 363 Activity ≤ 1 µM, 363 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on