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Biochemical CD73 Assay from US Patent US20240140979: "HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE"
Assay data:8 Active, 1 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Evaluation of PLK1 Kinase Activity In Vitro from US Patent US20240140962: "5,6-DIHYDROTHIENO[3,4-H]QUINAZOLINE COMPOUND"
Assay data:16 Active, 1 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 16 Tested
Menin-MLL In Vitro Inhibitory Activity from US Patent US20240140953: "INHIBITORS OF MENIN-MLL INTERACTION"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Radiometric Assay from US Patent US20240140952: "INHIBITORS AND DEGRADERS OF JANUS KINASE 2"
Assay data:15 Active, 9 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested
DGAT2 Enzymatic Activity Assay from US Patent US20240140938: "PREPARATION OF TETRAHYDROINDAZOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS"
Assay data:98 Active, 4 Activity ≤ 1 nM, 88 Activity ≤ 1 µM, 121 Tested
In Vitro PDHK1 Activity Assay from US Patent US20240140933: "OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER"
Assay data:63 Active, 63 Activity ≤ 1 µM, 63 Tested
Assay of Full-Length SHP2 Phosphatase Activity Assay from US Patent US20240140931: "TRICYCLIC COMPOUNDS AND USES THEREOF"
Assay data:264 Active, 82 Activity ≤ 1 nM, 272 Activity ≤ 1 µM, 272 Tested
Kinetic Labeling Experiments of Ibrutinib Derivatives with BTK from US Patent US20240139326: "METHACRYLAMIDES PROTEIN BINDERS AND USES THEREOF"
Assay data:10 Active, 8 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Biochemical CD73 Assay from US Patent US20240140980: "HETEROCYCLIC INHIBITORS OF CD73 FOR TREATMENT OF DISEASE"
Assay data:29 Active, 15 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 29 Tested
TR-FRET assay from US Patent US20240139189: "N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT"
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
In Vitro OGG1 Activity Assay from US Patent US11970474: "Substituted benzodiazoles and use thereof in therapy"
Assay data:325 Active, 6 Activity ≤ 1 nM, 192 Activity ≤ 1 µM, 325 Tested
hERG Assay from US Patent US11970463: "Compounds and their use"
Assay data:1 Active, 35 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Biochemical Kinase Assay Protocol (JAK) from US Patent US20240132525: "BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF"
Assay data:90 Active, 39 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested
Bioluminescence Resonance Energy Transfer (BRET) Assay from US Patent US20240132519: "NRF2-ACTIVATING COMPOUND"
Assay data:35 Active, 24 Activity ≤ 1 nM, 35 Activity ≤ 1 µM, 35 Tested
Enzymatic Inhibitory Activity (IC50) Assay from US Patent US20240132517: "MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF"
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Human Sortilin Binding Assay from US Patent US20240132514: "PYRIDINE DERIVATIVES AS MODULATORS OF SORTILIN ACTIVITY"
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
In Vitro Evaluation of Inhibitory Activity Against Syk Protein Kinase from US Patent US20240132503: "SALT FORM AND CRYSTAL FORM OF PYRAZOLE SUBSTITUTED IMIDAZO[1,2- A]QUINOXALINE DERIVATIVE"
PD-L1 Binding Assay from US Patent US20240132491: "INDOLINE COMPOUND"
In Vitro Enzymatic Inhibitory Activity Assay from US Patent US20240132489: "AROMATIC HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF"
Assay data:55 Active, 55 Activity ≤ 1 µM, 55 Tested
LPD Assay with 30 min preincubation from US Patent US20240132480: "INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE"
Assay data:27 Active, 27 Activity ≤ 1 µM, 27 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
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