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Iron clearing efficiency in monkey at 150 umol/kg
Assay data:9 Tested
SummaryPubMed Citation
Maximum plasma concentration after peroral administration of compound at dose of 0.5 mg/kg in female monkeys was determined
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Cmax in monkey at 2.5 mg/kg, po
AUC in monkey at 2.5 mg/kg, po
Assay data:1 Tested
AUC in monkey at 2.5 mg/kg, iv
AUC in monkey at 3 mg/kg, po
AUC in monkey at 2 mg/kg, po
Assay data:2 Tested
Volume of distribution was observed in monkey after intravenous administration of 1-5 mg/kg
Assay data:5 Tested
Half life in rhesus Monkey
Plasma concentration reached maximum value at a dose of 10 mg/kg (po. and iv.) administered into monkey
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Plasma concentration reached maximum value in monkey after treatment with 10 mg/kg (po. and iv.)
Maximum concentration after intratracheal dose at administration of 0.1 mg/kg in rhesus monkey
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Maximum concentration after intravenous dose at administration of 1 mg/kg in rhesus monkey
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Maximum concentration after oral dose at administration of 10 mg/kg in rhesus monkey
Maximum concentration in monkey plasma after 10 mg/kg oral administration at 120 min
Maximum concentration was determined in monkey by iv/po dose at 10 mg/kg
Assay data:3 Tested
Maximum concentration was observed in monkey after oral dosage
Area under the plasma concentration-time curve in monkey after administration of intravenous dosage
Normalised Area under curve determined against adult Rhesus monkey at 2 mg/kg after peroral administration; (Number of rats = 3)
Plasma level area under the curve value in monkey after treatment with 10 mg/kg (po. and iv.)
Assay data:4 Tested
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