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Activation of recombinant mouse full length liver glucokinase expressed in Escherichia coli assessed as maximal activation incubated for 10 mins in presence of 12 mM glucose by plate reader analysis relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of recombinant mouse full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 12 mM glucose by plate reader analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activation Assay from US Patent US9409900: "Compound for increasing kinase active and application thereof"
Assay data:4 Active, 4 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Activation of glucokinase in mouse MIN6 cells assessed as increase in insulin secretion at 10 uM after 45 mins by ELISA relative to RO0281675
Assay data:14 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40 mins by Hoechst 33342 staining-based assay
Assay data:36 Active, 15 Activity ≤ 1 µM, 40 Tested
Assay data:13 Active, 6 Activity ≤ 1 µM, 30 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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