BioAssay by Target (List) for Gene (Select 10494) - PubChem BioAssay - NCBI

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Select item 19216251.

Inhibition of STK25 (unknown origin) by cellular target engagement assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1921625

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19216242.

Inhibition of STK25 (unknown origin) by FRET assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:4 Active, 3 Activity ≤ 1 µM, 8 Tested

AID:: 1921624

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19216233.

Inhibition of STK25 (unknown origin)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1921623

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18890374.

Inhibition of STK25 (unknown origin) at 1.0 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1889037

Summary PubMed Citation Related BioAssays by Target

Select item 18839385.

Inhibition of STK25 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1883938

Summary PubMed Citation Related BioAssays by Target

Select item 18354796.

YSK1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1835479

Summary Related BioAssays by Target

Select item 18351657.

STK25(h) Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1835165

Summary Related BioAssays by Target

Select item 18343348.

Inhibition of STK25 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1834334

Summary PubMed Citation Related BioAssays by Target

Select item 17943999.

KinomeScan assay: inhibition of YSK1

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:108 Tested

AID:: 1794399

Summary Related BioAssays by Target

Select item 179390410.

YSK1(ST25LHY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793904

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179285711.

STK25(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1792857

Summary Related BioAssays by Target

Select item 179247512.

STK25 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1792475

Summary Related BioAssays by Target

Select item 179119713.

STK25 (YSK1) Kinase screen

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1791197

Summary Related BioAssays by Target

Select item 179037714.

STK25 Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1790377

Summary Related BioAssays by Target

Select item 178946815.

STK25(h) Eurofins Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1789468

Summary Related BioAssays by Target

Select item 178752316.

STK25(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1787523

Summary Related BioAssays by Target

Select item 178656817.

STK25 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1786568

Summary Related BioAssays by Target

Select item 178609618.

YSK1 Kinase panel

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:1 Tested

AID:: 1786096

Summary Related BioAssays by Target

Select item 177986419.

Inhibition of NanoLuc-fused YSK1 (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assay

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:2 Tested

AID:: 1779864

Summary PubMed Citation Related BioAssays by Target

Select item 177985420.

Inhibition of wild-type human partial length YSK1 (V14 to H295 residues) expressed in bacterial expression system assessed as residual percent of control by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Serine/threonine-protein kinase 25

Assay data:2 Tested

AID:: 1779854

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (15)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (18)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (119)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (44)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (97)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (63)
BioAssays deposited by other experimentalists

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