BioAssay by Target (List) for Gene (Select 10902) - PubChem BioAssay - NCBI

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Select item 19582941.

Binding affinity to BRD8 bromodomain 2 (unknown origin) by BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:4 Tested

AID:: 1958294

Summary PubMed Citation Related BioAssays by Target

Select item 19582932.

Binding affinity to BRD8 bromodomain 1 (unknown origin) by BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:4 Tested

AID:: 1958293

Summary PubMed Citation Related BioAssays by Target

Select item 19492223.

Binding affinity to BRD8 bromodomain (unknown origin) incubated for 60 mins by TR-FRET assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1949222

Summary PubMed Citation Related BioAssays by Target

Select item 19491504.

Displacement of biotinylated JQ1 from BRD8 bromodomain (unknown origin) incubated for 20 mins by AlphaLISA assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1949150

Summary PubMed Citation Related BioAssays by Target

Select item 17881355.

BRD8(2) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1788135

Summary Related BioAssays by Target

Select item 17881346.

BRD8(1) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1788134

Summary Related BioAssays by Target

Select item 17880797.

BRD8(2) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1788079

Summary Related BioAssays by Target

Select item 17880788.

BRD8(1) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1788078

Summary Related BioAssays by Target

Select item 17879609.

BRD8 (BD2) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1787960

Summary Related BioAssays by Target

Select item 178795910.

BRD8 (BD1) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1787959

Summary Related BioAssays by Target

Select item 178779511.

BRD8 (2) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1787795

Summary Related BioAssays by Target

Select item 178779412.

BRD8 (1) DiscoverX BROMOscan

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1787794

Summary Related BioAssays by Target

Select item 176826213.

Inhibition of human BRD8 BD2 at 10 uM by DiscoverX assay relative to control

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1768262

Summary PubMed Citation Related BioAssays by Target

Select item 176826114.

Inhibition of human BRD8 BD1 at 10 uM by DiscoverX assay relative to control

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1768261

Summary PubMed Citation Related BioAssays by Target

Select item 167002915.

Thermal Shift Assay. Domain start/stop: S759-K917

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1670029

Summary Related BioAssays by Target

Select item 166188116.

Inhibition of BRD8 bromodomain 2 (unknown origin) by BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1661881

Summary PubMed Citation Related BioAssays by Target

Select item 166188017.

Inhibition of BRD8 bromodomain 1 (unknown origin) by BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1661880

Summary PubMed Citation Related BioAssays by Target

Select item 165225318.

Binding affinity to human partial length BRD8 BD2 (D1095 to F1235 residues) expressed in mammalian expression system BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1652253

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 165225219.

Binding affinity to human partial length BRD8 BD1 (S700 to F854 residues) expressed in mammalian expression system BROMOscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1652252

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 153567020.

Binding affinity to BRD8 bromodomain 2 (unknown origin) after 1 hr by bromoscan assay

Source:: ChEMBL

Protein Target:: Bromodomain-containing protein 8

Assay data:1 Tested

AID:: 1535670

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (4)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (27)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (32)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (23)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (22)
BioAssays deposited by other experimentalists

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