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Binding affinity to GlyT1 in rat brain corpus callosum at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 10 mM GlyT1 substrate glycine relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]glycine from rat GlyT1 expressed in rat C6 cells after 30 mins by scintillation counting
Assay data:13 Active, 6 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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