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Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of m-TOR at ser2481 at 1 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Activation of ClC-3 in human CNE2Z cells assessed as increase in chloride current in outward and inward direction at +80mV holding potential at 1 uM by whole-cell patch clamp method
Assay data:1 Active, 2 Tested
Activation of ClC-3 in SV40-transformed human NP69 cells assessed as increase in chloride current density at +80mV holding potential at 1 uM by whole-cell patch clamp method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of Akt at Thr308 at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of m-TOR at ser2481 at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of m-TOR at ser2448 at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in m-TOR level at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of Akt at ser473 at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in Akt level at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
Activation of ClC-3 in human CNE2Z cells assessed as decrease in PI3K P110alpha level at 1 uM after 24 hrs by Western blot analysis in presence of ClC-3 siRNA
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of m-TOR at ser2448 at 1 uM after 24 hrs by Western blot analysis
Activation of ClC-3 in human CNE2Z cells assessed as decrease in m-TOR level at 1 uM after 24 hrs by Western blot analysis
Activation of ClC-3 in human CNE2Z cells assessed as decrease in phosphorylation of Akt at Thr308 at 1 uM after 24 hrs by Western blot analysis
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