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Antagonist activity at TLR3 in mouse BMDM assessed as inhibition of poly I:C-stimulated TNFalpha production at 25 uM preincubated for 1 hr followed by poly I:C stimulation for 11 hrs by ELISA
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at TLR3 in mouse RAW264.7 cells assessed as inhibition of Poly(I:C)-induced receptor activation by measuring NO production at 0.5 uM after 24 hrs
Assay data:1 Tested
SummaryRelated BioAssays by Target
Antagonist activity at TLR3 in mouse RAW264.7 cells assessed as inhibition of Poly(I:C)-induced receptor activation by measuring NO production at 3 uM after 24 hrs
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
TLR-pathway-mouse_LPS ligand_TNF readout
Assay data:130 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
TLR-pathway-mouse_P3C ligand_TNF readout
Assay data:115 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_NFkB readout
Assay data:137 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_NFkB readout
Assay data:147 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_TNF readout
TLR-pathway-mouse_P3C ligand_NFkB readout
Assay data:128 Active, 756 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha phosphorylation up to 90 mins by Western blot analysis
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced IkappaBalpha degradation up to 90 mins by Western blot analysis
Inhibition of TRIF recruitment to TLR3 in C57BL/6 mouse BMDM cells assessed as inhibition of pI:pC-induced p38 MAPK activity up to 90 mins
Inhibition of TLR3 in poly(I:C)-stimulated mouse RAW264.7 cells at 0.6 uM after 24 hrs
Inhibition TLR3-mediated NO production in mouse RAW264.7 cells at 300 uM
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