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Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 25 uM after 5 mins by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of IKKbeta in primary type-2 collagen immunized mouse splenocytes assessed as inhibition of TNFalpha production at 10 uM after 72 hrs by ELISA
Assay data:11 Active, 1 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of LPS/IFNgamma-induced IKKbeta phosphorylation in mouse BV2 cells at 1 to 4 uM pre-incubated for 30 mins before LPS/IFNgamma challenge for 1 hr by Western blot method
TLR-pathway-mouse_LPS ligand_TNF readout
Assay data:130 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
TLR-pathway-mouse_P3C ligand_TNF readout
Assay data:115 Active, 756 Tested
TLR-pathway-mouse_LPS ligand_NFkB readout
Assay data:137 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_NFkB readout
Assay data:147 Active, 756 Tested
TLR-pathway-mouse_R848 ligand_TNF readout
TLR-pathway-mouse_P3C ligand_NFkB readout
Assay data:128 Active, 756 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha phosphorylation at 50 uM up to 90 mins by Western blot analysis
Assay data:2 Active, 5 Tested
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced IkappaBalpha degradation at 50 uM up to 90 mins by Western blot analysis
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 50 uM up to 90 mins by Western blot analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha degradation at 50 uM up to 90 mins by Western blot analysis
Inhibition of LPS-induced IKKbeta phosphorylation in mouse RAW264.7 cells preincubated for 6 hrs followed by LPS challenge measured after 30 mins by ELISA method
Assay data:1 Tested
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced phosphorylation at 25 uM after 5 mins by Western blot analysis
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of LPS-induced RelA phosphorylation at 25 uM after 5 mins by Western blot analysis
Inhibition of IKKbeta in C57BL/6 mouse BMDM cells assessed as inhibition of TNFalpha-induced IkappaBalpha phosphorylation at 25 uM after 5 mins by Western blot analysis
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