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ACE(HU_AMTCH400) Eurofins SafetyScreen44 (BI)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Binding affinity to angiotensin-converting enzyme (unknown origin) assessed as inhibition constant
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to angiotensin-converting enzyme (unknown origin) assessed as Km
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of angiotensin-converting enzyme (unknown origin)
Assay data:21 Active, 20 Activity ≤ 1 µM, 23 Tested
Inhibition of recombinant human ACE catalytic activity measured up to 150 uM
Assay data:2 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of ACE (unknown origin) using tripeptide Hip-His-Leu-OH as substrate incubated for 4 mins by fluorimetric method
Inhibition of ACE (unknown origin)
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Enzyme Inhibition Assays (Assay 1) from US Patent US20230285340: "NEPRILYSIN INHIBITORS"
Assay data:52 Active, 26 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 52 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Neprilysin Inhibition Assay from US Patent US20230285340: "NEPRILYSIN INHIBITORS"
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Enzyme Inhibition Assay from US Patent US11547687: "Neprilysin inhibitors"
Assay data:59 Active, 25 Activity ≤ 1 nM, 59 Activity ≤ 1 µM, 59 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of ACE in human MNCs assessed as maximum inhibition using substrate Mca-RPGFSAFK (Dnp)-OH as substrate by fluorescence plate reader assay relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human ACE using Mca-RPGFSAFK (Dnp)- OH as substrate by fluorescence plate reader assay
Assay data:1 Active, 3 Tested
Inhibition of recombinant human ACE assessed as maximum inhibition using Mca-RPGFSAFK (Dnp)-OH as substrate by fluorescence plate reader assay relative to control
Inhibition of angiotensin converting enzyme (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
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