Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Evaluation of Compounds as Inhibitors of GABA-AT from US Patent US10800753: "Tetrahydrothiophene-based GABA aminotransferase inactivators and analogs thereof for treating neurological disorders"
Assay data:7 Tested
SummaryRelated BioAssays by Target
Biochemical assay from US Patent US10189807: "Tetrahydrothiophene-based GABA aminotransferase inactivators"
Inactivation of GABA-AT (unknown origin) assessed as partition ratio
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Covalent inhibition of GABA-AT (unknown origin) assessed as kinact/Ki ratio
Competitive inhibition of GABA aminotransferase (unknown origin)
Assay data:2 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to GABA transaminase (unknown origin) at 10 uM
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of GABA transaminase (unknown origin)
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of GABA-AT (unknown origin)
Assay data:17 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Ratio of compound Kinact/Ki to vigabatrin Kinact/Ki for GABA-AT
Inactivation of GABA-AT
Inhibition of GABA transaminase at 10 uM by CEREP assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on