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Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assay
Assay data:18 Active, 2 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assay relative to control ATRA
Assay data:23 Tested
SummaryPubMed CitationRelated BioAssays by Target
Mouse Retinoic acid receptor-gamma (1B. Retinoic acid receptors)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Antagonist activity at Gal4-fused mouse RAR-gamma transfected in human HeLa cells after 12 hrs by luciferase reporter gene assay
Assay data:3 Active, 3 Tested
Agonist activity at Gal4-fused mouse RAR-gamma transfected in human HeLa cells at 1 uM after 12 hrs by luciferase reporter gene assay
Assay data:3 Tested
Agonist activity at Gal4-fused mouse RAR-gamma transfected in human HeLa cells at 10 uM after 12 hrs by luciferase reporter gene assay
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Agonist activity at yeast GAL4 fused mouse RARgamma ligand binding domain expressed in HeLa cells assessed as receptor transactivation by luciferase reporter gene assay
Assay data:3 Active, 6 Tested
Antagonist activity at yeast GAL4 fused mouse RARgamma ligand binding domain expressed in HeLa cells assessed as inhibition of TTNPB-induced receptor transactivation by luciferase reporter gene assay
Assay data:5 Active, 8 Tested
Antagonist activity at mouse RARgamma expressed in COS-1 cells assessed as inhibition of ATRA-induced transactivation by luciferase reporter gene assay
Assay data:2 Tested
Dissociation constant for binding to Retinoic acid receptor gamma;NA=not active
Assay data:1 Tested
Dissociation constant for binding to Retinoic acid receptor gamma
Assay data:6 Active, 3 Activity ≤ 1 µM, 7 Tested
Inhibition of binding to retinoid A receptor RAR gamma
Assay data:5 Active, 7 Activity ≤ 1 µM, 8 Tested
Inhibition of binding to murine Retinoic acid receptor RAR gamma
Assay data:5 Active, 5 Activity ≤ 1 µM, 6 Tested
Transcriptional activation in CV-1 cells expressing retinoic A receptor RAR gamma
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR gamma
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
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