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Inhibition of mouse Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis
Assay data:17 Active, 8 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of mouse Nav1.7/beta1/beta2 expressed in HEK293A cells assessed as dissociation half life at 100 nM with -120 mV holding potential by whole cell manual patch clamp method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mouse Nav1.7/beta1/beta2 expressed in HEK293A cells with -120 mV holding potential by whole cell manual patch clamp method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of mouse Nav1.5/beta1/beta2 expressed in HEK293A cells with -140 mV holding potential by whole cell manual patch clamp method
Inhibition of mouse Nav1.1/beta1/beta2 expressed in HEK293A cells with -120 mV holding potential by whole cell manual patch clamp method
Inhibition of mouse Nav1.7/beta1/beta2 expressed in HEK293A cells at 0.3 uM with -120 mV holding potential by whole cell manual patch clamp method relative to control
Inhibition of mouse Nav1.5/beta1/beta2 expressed in HEK293A cells at 100 uM with -140 mV holding potential by whole cell manual patch clamp method relative to control
Inhibition of mouse Nav1.1/beta1/beta2 expressed in HEK293A cells at 100 uM with -120 mV holding potential by whole cell manual patch clamp method relative to control
Inhibition of mouse NaV1.7/beta1/beta2 expressed in HEK293A cells by Ionworks high-throughput electrophysiology method
Assay data:16 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 19 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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