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Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay relative to Zn+2
Assay data:4 Tested
Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins relative to Zn+2
Agonist activity at GPR39 in human HT-29 cells assessed as increase in intracellular Ca2+ mobilization after 72 hrs by FLIPR assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization after 72 hrs by FLIPR assay in presence of siRNA
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Agonist activity at GPR39 in human islets assessed as 2.8 mM glucose-stimulated insulin secretion up to 10 uM after 0.75 hrs
Agonist activity at GPR39 in human islets assessed as 11.2 mM glucose-stimulated insulin secretion up to 10 uM after 1 hr
Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization up to 30 uM after 72 hrs by FLIPR assay
Assay data:2 Tested
Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation up to 30 uM
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
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