BioAssay by Target (List) for Gene (Select 4593) - PubChem BioAssay - NCBI

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Select item 19583751.

Inhibition of MuSK (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:3 Tested

AID:: 1958375

Summary PubMed Citation Related BioAssays by Target

Select item 19142062.

Selectivity interaction (ScanMAX (DiscoverX)) EUB0000005b MUSK

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914206

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19135653.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b MUSK

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1913565

Summary Related BioAssays by Target

Select item 19135104.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a MUSK

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1913510

Summary Related BioAssays by Target

Select item 19006125.

Inhibition of MUSK (unknown origin) at 0.1 uM relative to control

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1900612

Summary PubMed Citation Related BioAssays by Target

Select item 18545636.

Inhibition of MUSK (unknown origin) at 10 nM relative to control

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1854563

Summary PubMed Citation Related BioAssays by Target

Select item 18501077.

Inhibition of MUSK (unknown origin) by Nano-syn mobility shift assay

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Active, 1 Tested

AID:: 1850107

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18356008.

MUSK DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1835600

Summary Related BioAssays by Target

Select item 18350669.

MuSK(h) Kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1835066

Summary Related BioAssays by Target

Select item 183477610.

MuSK(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1834776

Summary Related BioAssays by Target

Select item 183423511.

Inhibition of MUSK (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1834235

Summary PubMed Citation Related BioAssays by Target

Select item 183022612.

Inhibition of human MUSK expressed in baculovirus expression system by mobility shift assay

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1830226

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 183021313.

Inhibition of human MUSK expressed in baculovirus expression system at 0.3 uM by mobility shift assay

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1830213

Summary PubMed Citation Related BioAssays by Target

Select item 181632914.

Inhibition of human recombinant MuSK assessed as reduction in substrate phosphorylation at 500 nM using ATP and Ulight-CKKSRGDYMTMQIG (IRS-1) incubated for 60 min by LANCE detection method

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1816329

Summary PubMed Citation Related BioAssays by Target

Select item 181632815.

Inhibition of human recombinant MuSK assessed as reduction in substrate phosphorylation at 50 nM using ATP and Ulight-CAGAGAIETDKEYYTVKD as substrate incubated for 120 min by LANCE detection method

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1816328

Summary PubMed Citation Related BioAssays by Target

Select item 179421316.

KinomeScan assay: inhibition of MUSK

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:108 Tested

AID:: 1794213

Summary Related BioAssays by Target

Select item 179374517.

MUSK(MUSKLGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793745

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179345718.

MUSK(MUSKLGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793457

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179316319.

MUSK(MUSKLGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793163

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179276920.

MuSK(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Muscle, skeletal receptor tyrosine-protein kinase

Assay data:1 Tested

AID:: 1792769

Summary Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (22)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (20)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (24)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (158)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (127)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (73)
BioAssays deposited by other experimentalists

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